Lypd1 - Ly6/Plaur domain containing 1 Gene

Also Known as Lynx2; Lypdc1; 2700050C12Rik; C530008O16Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 72585

Summary

Enables acetylcholine receptor binding activity and acetylcholine receptor inhibitor activity. Acts upstream of or within several processes, including acetylcholine receptor signaling pathway; behavioral fear response; and negative regulation of protein localization to plasma membrane. Located in membrane. Is expressed in several structures, including alimentary system; limb; nervous system; sensory organ; and skin. Orthologous to human LYPD1 (LY6/PLAUR domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]

Lypd1 Products (3)

mRNA Protein Name
NM_001311089.1 NP_001298018.1 ly6/PLAUR domain-containing protein 1 isoform b
NM_001311090.1 NP_001298019.1 ly6/PLAUR domain-containing protein 1 isoform b
NM_145100.4 NP_659568.2 ly6/PLAUR domain-containing protein 1 isoform a precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables acetylcholine receptor binding IDA
IDA: Inferred from direct assay
26276394 MGI
enables acetylcholine receptor binding IPI
IPI: Inferred from physical interaction
19246390 MGI
enables acetylcholine receptor inhibitor activity IDA
IDA: Inferred from direct assay
26276394 MGI
enables acetylcholine receptor inhibitor activity IMP
IMP: Inferred from mutant phenotype
19246390 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
19246390 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within acetylcholine receptor signaling pathway IDA
IDA: Inferred from direct assay
26276394 MGI
acts upstream of or within behavioral fear response IMP
IMP: Inferred from mutant phenotype
19246390 MGI
acts upstream of or within negative regulation of protein localization to plasma membrane IDA
IDA: Inferred from direct assay
26276394 MGI
acts upstream of protein localization to plasma membrane IDA
IDA: Inferred from direct assay
26276394 MGI
acts upstream of or within response to nicotine IMP
IMP: Inferred from mutant phenotype
19246390 MGI
acts upstream of or within synaptic transmission, cholinergic IDA
IDA: Inferred from direct assay
19246390 MGI
Cellular Component GO Annotation Evidence References Source
located in membrane IDA
IDA: Inferred from direct assay
19246390 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ly6/PLAUR domain-containing protein 1

  • ly-6/neurotoxin-like protein 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07915 LYPD1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lypd1 NCBI NCBI:116372