Tdrkh - tudor and KH domain containing protein Gene

Mus musculus

Also known as Tdrd2; 2700091C21Rik

Gene ID: 72634 | Gene type: protein coding

About Tdrkh

Summary

Predicted to enable RNA binding activity. Involved in fertilization; gamete generation; and piRNA metabolic process. Located in mitochondrion; pi-body; and piP-body. Is expressed in central nervous system; reproductive system; and retina. Orthologous to human TDRKH (tudor and KH domain containing). [provided by Alliance of Genome Resources, Apr 2022]

Tdrkh Products(5)

mRNA	Protein	Name
NM_001357711.1	NP_001344640.1	tudor and KH domain-containing protein isoform 1
NM_001357712.1	NP_001344641.1	tudor and KH domain-containing protein isoform 1
NM_001357713.1	NP_001344642.1	tudor and KH domain-containing protein isoform 2
NM_001357714.1	NP_001344643.1	tudor and KH domain-containing protein isoform 3
NM_028307.2	NP_082583.1	tudor and KH domain-containing protein isoform 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	19918066	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in fertilization	IMP IMP: Inferred from mutant phenotype	23714778	MGI
involved in male meiotic nuclear division	IMP IMP: Inferred from mutant phenotype	23714778	MGI
involved in piRNA processing	IMP IMP: Inferred from mutant phenotype	23714778	MGI
involved in spermatogenesis	IMP IMP: Inferred from mutant phenotype	23714778	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in cytoplasm	IDA IDA: Inferred from direct assay	19918066	MGI
located in mitochondrion	IDA IDA: Inferred from direct assay	23714778	MGI
located in pi-body	IDA IDA: Inferred from direct assay	23714778	MGI
located in piP-body	IDA IDA: Inferred from direct assay	23714778	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

tudor and KH domain-containing protein

tudor domain-containing protein 2

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14340	TDRKH Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Tdrkh	NCBI	NCBI:11022

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