Lime1 - Lck interacting transmembrane adaptor 1 Gene

Also Known as LIME; 2810038K19Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 72699

Summary

Enables protein kinase binding activity. Acts upstream of or within several processes, including B cell receptor signaling pathway; regulation of MAP kinase activity; and regulation of intracellular signal transduction. Part of B cell receptor complex. Is expressed in central nervous system and ganglia. Orthologous to human LIME1 (Lck interacting transmembrane adaptor 1). [provided by Alliance of Genome Resources, Apr 2022]

Lime1 Products (1)

mRNA Protein Name
NM_023684.2 NP_076173.1 lck-interacting transmembrane adapter 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
16249387 MGI
enables protein kinase binding IPI
IPI: Inferred from physical interaction
16249387 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within B cell receptor signaling pathway IDA
IDA: Inferred from direct assay
16249387 MGI
acts upstream of or within regulation of MAP kinase activity IMP
IMP: Inferred from mutant phenotype
16249387 MGI
acts upstream of or within regulation of canonical NF-kappaB signal transduction IMP
IMP: Inferred from mutant phenotype
16249387 MGI
acts upstream of or within regulation of non-canonical NF-kappaB signal transduction IMP
IMP: Inferred from mutant phenotype
16249387 MGI
acts upstream of or within regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IMP
IMP: Inferred from mutant phenotype
16249387 MGI
acts upstream of or within regulation of release of sequestered calcium ion into cytosol IMP
IMP: Inferred from mutant phenotype
16249387 MGI
acts upstream of or within regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
16249387 MGI
Cellular Component GO Annotation Evidence References Source
part of B cell receptor complex IDA
IDA: Inferred from direct assay
16249387 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

lck-interacting transmembrane adapter 1

  • lck-interacting molecule

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-N16520 Kaempferol 3-O-β-D-glucopyranoside 6′′-(3-hydroxy-3-methylglutarate) / Unkown
HY-RS07661 LIME1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W749649 Neomenthoglycol / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lime1 NCBI NCBI:54923