Lime1 - Lck interacting transmembrane adaptor 1 Gene

Mus musculus

Also known as LIME; 2810038K19Rik

Gene ID: 72699 | Gene type: protein coding

About Lime1

Summary

Enables protein kinase binding activity. Acts upstream of or within several processes, including B cell receptor signaling pathway; regulation of MAP kinase activity; and regulation of intracellular signal transduction. Part of B cell receptor complex. Is expressed in central nervous system and ganglia. Orthologous to human LIME1 (Lck interacting transmembrane adaptor 1). [provided by Alliance of Genome Resources, Apr 2022]

Lime1 Products(1)

mRNA	Protein	Name
NM_023684.2	NP_076173.1	lck-interacting transmembrane adapter 1 precursor

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	16249387	MGI
enables protein kinase binding	IPI IPI: Inferred from physical interaction	16249387	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within B cell receptor signaling pathway	IDA IDA: Inferred from direct assay	16249387	MGI
acts upstream of or within regulation of MAP kinase activity	IMP IMP: Inferred from mutant phenotype	16249387	MGI
acts upstream of or within regulation of canonical NF-kappaB signal transduction	IMP IMP: Inferred from mutant phenotype	16249387	MGI
acts upstream of or within regulation of non-canonical NF-kappaB signal transduction	IMP IMP: Inferred from mutant phenotype	16249387	MGI
acts upstream of or within regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	IMP IMP: Inferred from mutant phenotype	16249387	MGI
acts upstream of or within regulation of release of sequestered calcium ion into cytosol	IMP IMP: Inferred from mutant phenotype	16249387	MGI
acts upstream of or within regulation of transcription by RNA polymerase II	IMP IMP: Inferred from mutant phenotype	16249387	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
part of B cell receptor complex	IDA IDA: Inferred from direct assay	16249387	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

lck-interacting transmembrane adapter 1

lck-interacting molecule

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-N16520	Kaempferol 3-O-β-D-glucopyranoside 6′′-(3-hydroxy-3-methylglutarate)		/	Unkown
HY-RS07661	LIME1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-W749649	Neomenthoglycol		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Lime1	NCBI	NCBI:54923

Name
Email *

	Sorry, but the email address you supplied was invalid.