Tmem135 - transmembrane protein 135 Gene

Also Known as PMP52; 2810439K08Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 72759

Summary

Involved in regulation of mitochondrial fission. Acts upstream of or within response to cold and response to food. Located in lipid droplet; mitochondrion; and peroxisome. Orthologous to human TMEM135 (transmembrane protein 135). [provided by Alliance of Genome Resources, Apr 2022]

Tmem135 Products (3)

mRNA Protein Name
NM_001360745.1 NP_001347674.1 transmembrane protein 135 isoform b
NM_001360746.1 NP_001347675.1 transmembrane protein 135 isoform b
NM_028343.5 NP_082619.3 transmembrane protein 135 isoform a

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within mitochondrion organization IMP
IMP: Inferred from mutant phenotype
33064130 MGI
involved in regulation of mitochondrial fission IMP
IMP: Inferred from mutant phenotype
27863209 MGI
acts upstream of or within regulation of oxidative phosphorylation IMP
IMP: Inferred from mutant phenotype
33064130 MGI
acts upstream of or within response to cold IDA
IDA: Inferred from direct assay
21151927 MGI
acts upstream of or within response to food IDA
IDA: Inferred from direct assay
21151927 MGI
acts upstream of or within retinal pigment epithelium development IMP
IMP: Inferred from mutant phenotype
33064130 MGI
Cellular Component GO Annotation Evidence References Source
located in lipid droplet IDA
IDA: Inferred from direct assay
21151927 MGI
located in mitochondrion IDA
IDA: Inferred from direct assay
21151927 MGI
located in peroxisome IDA
IDA: Inferred from direct assay
17768142 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transmembrane protein 135

  • peroxisomal membrane protein 52

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14667 TMEM135 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tmem135 NCBI NCBI:65084