Rint1 - RAD50 interactor 1 Gene

Predicted to be involved in mitotic G2 DNA damage checkpoint signaling; regulation of ER to Golgi vesicle-mediated transport; and retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum. Predicted to act upstream of or within protein transport and vesicle-mediated transport. Predicted to be located in endoplasmic reticulum. Predicted to be part of Dsl1/NZR complex. Is expressed in several structures, including alimentary system; brain; connective tissue; genitourinary system; and hemolymphoid system gland. Human ortholog(s) of this gene implicated in infantile liver failure syndrome. Orthologous to human RINT1 (RAD50 interactor 1). [provided by Alliance of Genome Resources, Apr 2022]