Macrod2 - mono-ADP ribosylhydrolase 2 Gene

Also Known as 1110033L15Rik; 2610107G07Rik; 2900006F19Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 72899

Summary

Predicted to enable ADP-ribosylglutamate hydrolase activity and deacetylase activity. Acts upstream of or within brain development and response to bacterium. Predicted to be located in nucleolus. Predicted to be active in nucleoplasm. Is expressed in several structures, including alimentary system; brain; genitourinary system; immune system; and sensory organ. Orthologous to human MACROD2 (mono-ADP ribosylhydrolase 2). [provided by Alliance of Genome Resources, Apr 2022]

Macrod2 Products (34)

mRNA Protein Name
NM_001013802.4 NP_001013824.2 ADP-ribose glycohydrolase MACROD2 isoform 1
NM_001406384.1 NP_001393313.1 ADP-ribose glycohydrolase MACROD2 isoform 3
NM_001406385.1 NP_001393314.1 ADP-ribose glycohydrolase MACROD2 isoform 4
NM_001406386.1 NP_001393315.1 ADP-ribose glycohydrolase MACROD2 isoform 5
NM_001406387.1 NP_001393316.1 ADP-ribose glycohydrolase MACROD2 isoform 6
NM_001406388.1 NP_001393317.1 ADP-ribose glycohydrolase MACROD2 isoform 7
NM_001406389.1 NP_001393318.1 ADP-ribose glycohydrolase MACROD2 isoform 8
NM_001406390.1 NP_001393319.1 ADP-ribose glycohydrolase MACROD2 isoform 9
NM_001406391.1 NP_001393320.1 ADP-ribose glycohydrolase MACROD2 isoform 10
NM_001406392.1 NP_001393321.1 ADP-ribose glycohydrolase MACROD2 isoform 11
NM_001406393.1 NP_001393322.1 ADP-ribose glycohydrolase MACROD2 isoform 12
NM_001406394.1 NP_001393323.1 ADP-ribose glycohydrolase MACROD2 isoform 13
NM_001406395.1 NP_001393324.1 ADP-ribose glycohydrolase MACROD2 isoform 14
NM_001406396.1 NP_001393325.1 ADP-ribose glycohydrolase MACROD2 isoform 15
NM_001406397.1 NP_001393326.1 ADP-ribose glycohydrolase MACROD2 isoform 16
NM_001406398.1 NP_001393327.1 ADP-ribose glycohydrolase MACROD2 isoform 17
NM_028387.2 NP_082663.1 ADP-ribose glycohydrolase MACROD2 isoform 2
NM_001013802.4 NP_001013824.2 ADP-ribose glycohydrolase MACROD2 isoform 1
NM_001406384.1 NP_001393313.1 ADP-ribose glycohydrolase MACROD2 isoform 3
NM_001406385.1 NP_001393314.1 ADP-ribose glycohydrolase MACROD2 isoform 4
NM_001406386.1 NP_001393315.1 ADP-ribose glycohydrolase MACROD2 isoform 5
NM_001406387.1 NP_001393316.1 ADP-ribose glycohydrolase MACROD2 isoform 6
NM_001406388.1 NP_001393317.1 ADP-ribose glycohydrolase MACROD2 isoform 7
NM_001406389.1 NP_001393318.1 ADP-ribose glycohydrolase MACROD2 isoform 8
NM_001406390.1 NP_001393319.1 ADP-ribose glycohydrolase MACROD2 isoform 9
NM_001406391.1 NP_001393320.1 ADP-ribose glycohydrolase MACROD2 isoform 10
NM_001406392.1 NP_001393321.1 ADP-ribose glycohydrolase MACROD2 isoform 11
NM_001406393.1 NP_001393322.1 ADP-ribose glycohydrolase MACROD2 isoform 12
NM_001406394.1 NP_001393323.1 ADP-ribose glycohydrolase MACROD2 isoform 13
NM_001406395.1 NP_001393324.1 ADP-ribose glycohydrolase MACROD2 isoform 14
NM_001406396.1 NP_001393325.1 ADP-ribose glycohydrolase MACROD2 isoform 15
NM_001406397.1 NP_001393326.1 ADP-ribose glycohydrolase MACROD2 isoform 16
NM_001406398.1 NP_001393327.1 ADP-ribose glycohydrolase MACROD2 isoform 17
NM_028387.2 NP_082663.1 ADP-ribose glycohydrolase MACROD2 isoform 2

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in brain development IEP
IEP: Inferred from expression pattern
17586838 MGI
acts upstream of or within response to bacterium IEP
IEP: Inferred from expression pattern
23012479 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ADP-ribose glycohydrolase MACROD2

  • MACRO domain containing 2

  • MACRO domain-containing protein 2

  • O-acetyl-ADP-ribose deacetylase MACROD2

  • [Protein ADP-ribosylaspartate] hydrolase MACROD2

  • [Protein ADP-ribosylglutamate] hydrolase

  • [Protein ADP-ribosylglutamate] hydrolase MACROD2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-146248B TFMU-ADPr diammonium 98.78% Unkown
HY-146248 TFMU-ADPr / Unkown
HY-RS07946 MACROD2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Macrod2 NCBI NCBI:140733