Rps6ka5 - ribosomal protein S6 kinase, polypeptide 5 Gene

Also Known as MSK1; RLPK; RLSK; MSPK1; S6K-alpha-5; 3110005L17Rik; 6330404E13Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 73086

Summary

Enables ATP binding activity and protein serine/threonine kinase activity. Involved in intracellular signal transduction; protein phosphorylation; and regulation of transcription, DNA-templated. Located in nucleus. Orthologous to human RPS6KA5 (ribosomal protein S6 kinase A5). [provided by Alliance of Genome Resources, Apr 2022]

Rps6ka5 Products (2)

mRNA Protein Name
NM_001330702.1 NP_001317631.1 ribosomal protein S6 kinase alpha-5 isoform 2
NM_153587.3 NP_705815.1 ribosomal protein S6 kinase alpha-5 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables ATP binding IDA
IDA: Inferred from direct assay
12628924 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
19078967 MGI
enables protein serine/threonine kinase activity IDA
IDA: Inferred from direct assay
12628924 MGI
Biological Process GO Annotation Evidence References Source
involved in intracellular signal transduction IDA
IDA: Inferred from direct assay
12628924 MGI
involved in protein phosphorylation IDA
IDA: Inferred from direct assay
12628924 MGI
involved in regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
12628924 MGI
involved in regulation of postsynapse organization IDA
IDA: Inferred from direct assay
23077336 MGI
involved in regulation of postsynapse organization IMP
IMP: Inferred from mutant phenotype
23077336 MGI
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
12628924 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ribosomal protein S6 kinase alpha-5

  • 90 kDa ribosomal protein S6 kinase 5

  • RSK-like protein kinase

  • nuclear mitogen- and stress-activated protein kinase 1

Rps6ka5 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Rps6ka5 Q8C050 Rara Mus musculus P11416
Anti Bait CoIP
19078967
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12258 RPS6KA5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22026 Rps6ka5 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28544 Rps6ka5 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rps6ka5 NCBI NCBI:9252