2. Gene
  3. Sppl2b - signal peptide peptidase like 2B Gene

Sppl2b - signal peptide peptidase like 2B Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as PSL1; 3110056O03Rik

Gene ID: 73218 | Gene type: protein coding

About Sppl2b

Summary

Predicted to enable aspartic endopeptidase activity, intramembrane cleaving and protein homodimerization activity. Predicted to be involved in membrane protein ectodomain proteolysis; membrane protein intracellular domain proteolysis; and regulation of immune response. Predicted to be located in several cellular components, including cytoskeleton; endosome membrane; and nucleoplasm. Predicted to be active in Golgi-associated vesicle membrane and lysosomal membrane. Predicted to be integral component of cytoplasmic side of endoplasmic reticulum membrane and integral component of lumenal side of endoplasmic reticulum membrane. Is expressed in embryo. Orthologous to human SPPL2B (signal peptide peptidase like 2B). [provided by Alliance of Genome Resources, Apr 2022]

Sppl2b Products(3)

mRNA Protein Name
NM_001358803.1 NP_001345732.1 signal peptide peptidase-like 2B isoform 2 precursor
NM_001358804.1 NP_001345733.1 signal peptide peptidase-like 2B isoform 3 precursor
NM_175195.3 NP_780404.2 signal peptide peptidase-like 2B isoform 1 precursor
Protein Preferred Names Protein Names

signal peptide peptidase-like 2B

protein SPP-like 2B

protein SPPL2b

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-111360 SPL-707 Inhibitor 99.64% Unkown
HY-RS13705 SPPL2B Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sppl2b NCBI NCBI:56928