Dppa3 - developmental pluripotency-associated 3 Gene

Also Known as PCG7; PGC7; Stella; 2410075G02Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 73708

Summary

Enables methylated histone binding activity. Involved in negative regulation of DNA demethylation; protection of DNA demethylation of female pronucleus; and regulation of genetic imprinting. Acts upstream of or within embryonic cleavage. Located in cytoplasm; female pronucleus; and male pronucleus. Is expressed in several structures, including central nervous system; early conceptus; gonad; hindgut diverticulum; and primordial germ cell. Orthologous to human DPPA3 (developmental pluripotency associated 3). [provided by Alliance of Genome Resources, Apr 2022]

Dppa3 Products (1)

mRNA Protein Name
NM_139218.1 NP_631964.1 developmental pluripotency-associated protein 3

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables methylated histone binding IMP
IMP: Inferred from mutant phenotype
22722204 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
17143267 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within embryonic cleavage IMP
IMP: Inferred from mutant phenotype
15018652 MGI
involved in epigenetic programing of female pronucleus IDA
IDA: Inferred from direct assay
35541912 MGI
involved in epigenetic programing of female pronucleus IMP
IMP: Inferred from mutant phenotype
17143267 MGI
Cellular Component GO Annotation Evidence References Source
located in chromatin IDA
IDA: Inferred from direct assay
35541912 MGI
located in cytoplasm IDA
IDA: Inferred from direct assay
11900980 MGI
located in female pronucleus IDA
IDA: Inferred from direct assay
11900980 MGI
NOT located in male pronucleus IDA
IDA: Inferred from direct assay
22722204 MGI
located in male pronucleus IDA
IDA: Inferred from direct assay
11900980 MGI
located in nucleus IDA
IDA: Inferred from direct assay
11900980 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

developmental pluripotency-associated protein 3

  • compaction-associated protein 1

  • primordial germ cell 7

  • primordial germ cell protein 7

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03971 DPPA3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dppa3 NCBI NCBI:359787