Dtx2 - deltex 2, E3 ubiquitin ligase Gene

Mus musculus

Also known as Deltex2; 2610524D08Rik

Gene ID: 74198 | Gene type: protein coding

About Dtx2

Summary

Predicted to enable ubiquitin protein Ligase activity. Acts upstream of or within Notch signaling pathway. Predicted to be located in nuclear membrane. Predicted to be active in nucleoplasm. Is expressed in several structures, including alimentary system; brain; gonad; nasal cavity epithelium; and pharyngo-tympanic tube. Orthologous to human DTX2 (deltex E3 ubiquitin Ligase 2). [provided by Alliance of Genome Resources, Apr 2022]

Dtx2 Products(4)

mRNA	Protein	Name
NM_001256096.1	NP_001243025.1	probable E3 ubiquitin-protein ligase DTX2 isoform 1
NM_001256097.1	NP_001243026.1	probable E3 ubiquitin-protein ligase DTX2 isoform 3
NM_001256098.1	NP_001243027.1	probable E3 ubiquitin-protein ligase DTX2 isoform 3
NM_023742.2	NP_076231.1	probable E3 ubiquitin-protein ligase DTX2 isoform 2

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	11226752	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within Notch signaling pathway	IDA IDA: Inferred from direct assay	11226752	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

probable E3 ubiquitin-protein ligase DTX2

RING-type E3 ubiquitin transferase DTX2	deltex 2 homolog
mDTX2	protein deltex-2

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04039	DTX2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Dtx2	NCBI	NCBI:113878

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