Dtx2 - deltex 2, E3 ubiquitin ligase Gene

Also Known as Deltex2; 2610524D08Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 74198

Summary

Predicted to enable ubiquitin protein Ligase activity. Acts upstream of or within Notch signaling pathway. Predicted to be located in nuclear membrane. Predicted to be active in nucleoplasm. Is expressed in several structures, including alimentary system; brain; gonad; nasal cavity epithelium; and pharyngo-tympanic tube. Orthologous to human DTX2 (deltex E3 ubiquitin Ligase 2). [provided by Alliance of Genome Resources, Apr 2022]

Dtx2 Products (4)

mRNA Protein Name
NM_001256096.1 NP_001243025.1 probable E3 ubiquitin-protein ligase DTX2 isoform 1
NM_001256097.1 NP_001243026.1 probable E3 ubiquitin-protein ligase DTX2 isoform 3
NM_001256098.1 NP_001243027.1 probable E3 ubiquitin-protein ligase DTX2 isoform 3
NM_023742.2 NP_076231.1 probable E3 ubiquitin-protein ligase DTX2 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
11226752 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within Notch signaling pathway IDA
IDA: Inferred from direct assay
11226752 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

probable E3 ubiquitin-protein ligase DTX2

  • RING-type E3 ubiquitin transferase DTX2

  • deltex 2 homolog

  • mDTX2

  • protein deltex-2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04039 DTX2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dtx2 NCBI NCBI:113878