Eif4enif1 - eukaryotic translation initiation factor 4E nuclear import factor 1 Gene

Also Known as Clast4; D11Ertd166e; 2610509L04Rik; A930019J01Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 74203

Summary

Enables mRNA binding activity. Acts upstream of or within negative regulation of neuron differentiation; negative regulation of translation; and stem cell population maintenance. Located in P-body; cytosol; and nucleus. Is expressed in several structures, including cerebral cortex; early conceptus; epithelium; metanephros; and ovary. Orthologous to human EIF4ENIF1 (eukaryotic translation initiation factor 4E nuclear import factor 1). [provided by Alliance of Genome Resources, Apr 2022]

Eif4enif1 Products (4)

mRNA Protein Name
NM_001166547.1 NP_001160019.1 eukaryotic translation initiation factor 4E transporter isoform a
NM_001166548.1 NP_001160020.1 eukaryotic translation initiation factor 4E transporter isoform b
NM_001166549.1 NP_001160021.1 eukaryotic translation initiation factor 4E transporter isoform b
NM_023743.2 NP_076232.2 eukaryotic translation initiation factor 4E transporter isoform a

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables mRNA binding IDA
IDA: Inferred from direct assay
25456498 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
14651998 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within negative regulation of neuron differentiation IGI
IGI: Inferred from genetic interaction
25456498 MGI
acts upstream of or within negative regulation of translation IMP
IMP: Inferred from mutant phenotype
25456498 MGI
acts upstream of neuron differentiation IGI
IGI: Inferred from genetic interaction
25456498 MGI
acts upstream of or within stem cell population maintenance IGI
IGI: Inferred from genetic interaction
25456498 MGI
acts upstream of translation IMP
IMP: Inferred from mutant phenotype
25456498 MGI
Cellular Component GO Annotation Evidence References Source
located in P-body IDA
IDA: Inferred from direct assay
25456498 MGI
located in cytoplasm IDA
IDA: Inferred from direct assay
25456498 MGI
located in cytosol IDA
IDA: Inferred from direct assay
16343815 MGI
located in nucleus IDA
IDA: Inferred from direct assay
16343815 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

eukaryotic translation initiation factor 4E transporter

  • 4E-T

  • CD40 ligand-activated specific transcript 4

  • eIF4E transporter

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04280 EIF4ENIF1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Eif4enif1 NCBI NCBI:56478