2. Gene
  3. Myo18b - myosin XVIIIb Gene

Myo18b - myosin XVIIIb Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Gm448; 4932408L24Rik; 4933411E19Rik

Gene ID: 74376 | Gene type: protein coding

About Myo18b

Summary

Acts upstream of or within cardiac muscle cell development; in utero embryonic development; and vasculogenesis. Located in Z disc. Part of filamentous actin. Is expressed in several structures, including diaphragm; heart; and musculature. Human ortholog(s) of this gene implicated in Klippel-Feil syndrome 4. Orthologous to human MYO18B (Myosin XVIIIB). [provided by Alliance of Genome Resources, Apr 2022]

Myo18b Products(1)

mRNA Protein Name
NM_028901.2 NP_083177.2 unconventional myosin-XVIIIb
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within cardiac muscle cell development IMP
IMP: Inferred from mutant phenotype
18761673 MGI
acts upstream of or within in utero embryonic development IMP
IMP: Inferred from mutant phenotype
18761673 MGI
acts upstream of or within vasculogenesis IMP
IMP: Inferred from mutant phenotype
18761673 MGI
Cellular Component GO Annotation Evidence Reference Source
located in Z disc IDA
IDA: Inferred from direct assay
18761673 MGI
part of filamentous actin IDA
IDA: Inferred from direct assay
18761673 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

unconventional myosin-XVIIIb

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08935 MYO18B Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Myo18b NCBI NCBI:84700