Tdrd9 - tudor domain containing 9 Gene

Also Known as 4930441E05Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 74691

Summary

Predicted to enable RNA binding activity. Involved in fertilization; gamete generation; and piRNA metabolic process. Acts upstream of or within negative regulation of transposition. Located in nucleus and piP-body. Is expressed in germ cell of testis. Human ortholog(s) of this gene implicated in spermatogenic failure 30. Orthologous to human TDRD9 (tudor domain containing 9). [provided by Alliance of Genome Resources, Apr 2022]

Tdrd9 Products (2)

mRNA Protein Name
NM_029056.1 NP_083332.1 ATP-dependent RNA helicase TDRD9
NM_029056.1 NP_083332.1 ATP-dependent RNA helicase TDRD9

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables ATP hydrolysis activity IMP
IMP: Inferred from mutant phenotype
28633017 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
20059948 MGI
Biological Process GO Annotation Evidence References Source
involved in fertilization IMP
IMP: Inferred from mutant phenotype
20059948 MGI
involved in male meiosis I IMP
IMP: Inferred from mutant phenotype
28633017 MGI
involved in male meiotic nuclear division IMP
IMP: Inferred from mutant phenotype
20059948 MGI
involved in piRNA processing IMP
IMP: Inferred from mutant phenotype
20059948 MGI
involved in piRNA-mediated retrotransposon silencing by heterochromatin formation IMP
IMP: Inferred from mutant phenotype
28633017 MGI
acts upstream of or within retrotransposon silencing IMP
IMP: Inferred from mutant phenotype
27473657 MGI
involved in retrotransposon silencing by piRNA-directed DNA methylation IMP
IMP: Inferred from mutant phenotype
20059948 MGI
involved in spermatogenesis IMP
IMP: Inferred from mutant phenotype
20059948 MGI
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
20059948 MGI
located in piP-body IDA
IDA: Inferred from direct assay
20011505 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ATP-dependent RNA helicase TDRD9

  • putative ATP-dependent RNA helicase TDRD9

  • tudor domain-containing protein 9

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14339 TDRD9 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22852 Tdrd9 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29366 Tdrd9 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tdrd9 NCBI NCBI:122402