Mdga1 - MAM domain containing glycosylphosphatidylinositol anchor 1 Gene

Also Known as GPIM; Mamdc3; 1200011I03Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 74762

Summary

Involved in neuron migration. Acts upstream of or within cerebral cortex radially oriented cell migration. Predicted to be located in Golgi apparatus; membrane raft; and plasma membrane. Predicted to be anchored component of plasma membrane. Predicted to be active in GABA-ergic synapse. Is expressed in central nervous system and dorsal root ganglion. Orthologous to human MDGA1 (MAM domain containing glycosylphosphatidylinositol anchor 1). [provided by Alliance of Genome Resources, Apr 2022]

Mdga1 Products (2)

mRNA Protein Name
NM_001081160.1 NP_001074629.1 MAM domain-containing glycosylphosphatidylinositol anchor protein 1 isoform 2 precursor
NM_001368423.1 NP_001355352.1 MAM domain-containing glycosylphosphatidylinositol anchor protein 1 isoform 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
23358245 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within cerebral cortex radially oriented cell migration IMP
IMP: Inferred from mutant phenotype
21104742 MGI
acts upstream of or within inhibitory synapse assembly IDA
IDA: Inferred from direct assay
23358245 MGI
acts upstream of or within inhibitory synapse assembly IMP
IMP: Inferred from mutant phenotype
23358245 MGI
involved in neuron migration IDA
IDA: Inferred from direct assay
16641224 MGI
acts upstream of or within neuron migration IMP
IMP: Inferred from mutant phenotype
20473291 MGI
acts upstream of or within presynapse assembly IDA
IDA: Inferred from direct assay
23358245 MGI
acts upstream of or within regulation of protein binding IDA
IDA: Inferred from direct assay
23358245 MGI
Cellular Component GO Annotation Evidence References Source
is active in axon IDA
IDA: Inferred from direct assay
23358245 MGI
is active in cell surface IDA
IDA: Inferred from direct assay
23358245 MGI
is active in dendrite IDA
IDA: Inferred from direct assay
23358245 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

MAM domain-containing glycosylphosphatidylinositol anchor protein 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08258 MDGA1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mdga1 NCBI NCBI:266727