Sap25 - sin3 associated polypeptide Gene

Mus musculus

Gene ID: 751865 | Gene type: protein coding

About Sap25

Summary

Predicted to be involved in regulation of transcription, DNA-templated. Predicted to be located in cytoplasm and nucleus. Orthologous to human SAP25 (Sin3A associated protein 25). [provided by Alliance of Genome Resources, Apr 2022]

Sap25 Products(1)

mRNA	Protein	Name
NM_001081962.2	NP_001075431.2	histone deacetylase complex subunit SAP25

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	16449650	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in negative regulation of DNA-templated transcription	IMP IMP: Inferred from mutant phenotype	16449650	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
is active in nucleus	IDA IDA: Inferred from direct assay	16449650	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

histone deacetylase complex subunit SAP25

25 kDa Sin3-associated polypeptide	mSin3A-binding protein
sin3 corepressor complex subunit SAP25	sin3A-binding protein, SAP25

Sap25 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	Sap25	Q1EHW4	Sin3a	Mus musculus	Q60520	IF	16449650
Intra	Sap25	Q1EHW4	Sin3a	Mus musculus	Q60520	Y2H	16449650
Intra	Sap25	Q1EHW4	Sin3a	Mus musculus	Q60520	Pull Down	16449650

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12439	SAP25 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Sap25	NCBI	NCBI:100316904

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