Rnf19b - ring finger protein 19B Gene

Also Known as Ibrdc3; 4930534K13Rik; 4930555L03Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 75234

Summary

Predicted to enable ubiquitin binding activity; ubiquitin conjugating enzyme binding activity; and ubiquitin protein Ligase activity. Acts upstream of or within natural killer cell mediated cytotoxicity. Located in cytolytic granule. Orthologous to human RNF19B (ring finger protein 19B). [provided by Alliance of Genome Resources, Apr 2022]

Rnf19b Products (2)

mRNA Protein Name
NM_001368763.1 NP_001355692.1 E3 ubiquitin-protein ligase RNF19B isoform 1
NM_029219.2 NP_083495.1 E3 ubiquitin-protein ligase RNF19B isoform 2

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within natural killer cell mediated cytotoxicity IMP
IMP: Inferred from mutant phenotype
19915045 MGI
acts upstream of or within type II interferon production IMP
IMP: Inferred from mutant phenotype
19915045 MGI
Cellular Component GO Annotation Evidence References Source
located in cytolytic granule IDA
IDA: Inferred from direct assay
19915045 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase RNF19B

  • IBR domain containing 3

  • IBR domain-containing protein 3

  • natural killer lytic-associated molecule

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12073 RNF19B Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rnf19b NCBI NCBI:127544