Med25 - mediator complex subunit 25 Gene

Also Known as ESTM2; 2610034E13Rik; 2610529E18Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 75613

Summary

Enables retinoid X receptor binding activity. Acts upstream of or within positive regulation of transcription by RNA polymerase II. Part of transcription regulator complex. Is expressed in central nervous system; incisor; submandibular gland primordium; and tail dorsal root ganglion. Orthologous to human MED25 (mediator complex subunit 25). [provided by Alliance of Genome Resources, Apr 2022]

Med25 Products (4)

mRNA Protein Name
NM_001331206.1 NP_001318135.1 mediator of RNA polymerase II transcription subunit 25 isoform 2
NM_001331207.1 NP_001318136.1 mediator of RNA polymerase II transcription subunit 25 isoform 3
NM_001331208.1 NP_001318137.1 mediator of RNA polymerase II transcription subunit 25 isoform 4
NM_029365.3 NP_083641.1 mediator of RNA polymerase II transcription subunit 25 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables nuclear retinoic acid receptor binding IPI
IPI: Inferred from physical interaction
17641689 MGI
enables nuclear retinoid X receptor binding IPI
IPI: Inferred from physical interaction
17641689 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
21427722 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within positive regulation of transcription by RNA polymerase II IGI
IGI: Inferred from genetic interaction
21427722 MGI
acts upstream of transcription by RNA polymerase II IGI
IGI: Inferred from genetic interaction
21427722 MGI
Cellular Component GO Annotation Evidence References Source
part of transcription regulator complex IPI
IPI: Inferred from physical interaction
21427722 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

mediator of RNA polymerase II transcription subunit 25

  • mediator of RNA polymerase II transcription, subunit 9 homolog

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-158104 LPPM-8 Inhibitor / Unkown
HY-RS08296 MED25 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS08307 MED9 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18774 Med9 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Med25 NCBI NCBI:81857