Samd7 - sterile alpha motif domain containing 7 Gene

Mus musculus

Also known as 4930597A01Rik

Gene ID: 75953 | Gene type: protein coding

About Samd7

Summary

Predicted to enable chromatin binding activity and histone binding activity. Involved in negative regulation of gene expression. Located in cytoplasm and nucleus. Is expressed in central nervous system; dorsal root ganglion; liver; metanephros; and neural retina. Orthologous to human SAMD7 (sterile alpha motif domain containing 7). [provided by Alliance of Genome Resources, Apr 2022]

Samd7 Products(1)

mRNA	Protein	Name
NM_029489.4	NP_083765.2	sterile alpha motif domain-containing protein 7

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables DNA-binding transcription repressor activity, RNA polymerase II-specific	IMP IMP: Inferred from mutant phenotype	28900001	MGI
enables protein binding	IPI IPI: Inferred from physical interaction	28900001	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in negative regulation of gene expression	IDA IDA: Inferred from direct assay	23565263	MGI
involved in negative regulation of gene expression, epigenetic	IMP IMP: Inferred from mutant phenotype	28900001	MGI
involved in retinal rod cell development	IMP IMP: Inferred from mutant phenotype	33603070	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
part of PRC1 complex	IDA IDA: Inferred from direct assay	28900001	MGI
located in cytoplasm	IDA IDA: Inferred from direct assay	23565263	MGI
located in nucleus	IDA IDA: Inferred from direct assay	23565263	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

sterile alpha motif domain-containing protein 7

SAM domain-containing protein 7

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12429	SAMD7 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Samd7	NCBI	NCBI:344658

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