SAMD7 - sterile alpha motif domain containing 7 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 344658

About SAMD7

This gene has 3 transcripts (splice variants), 205 orthologues and 18 paralogues. Low expression observed in reference dataset.

Summary

Predicted to enable chromatin binding activity and histone binding activity. Predicted to be involved in negative regulation of transcription, DNA-templated. Predicted to be located in cytoplasm. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

SAMD7 Products (2)

mRNA Protein Name
NM_001304366.2 NP_001291295.1 sterile alpha motif domain-containing protein 7
NM_182610.4 NP_872416.1 sterile alpha motif domain-containing protein 7

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SAMD7 Protein Structure

SAM_1

SAM_1: SAM domain (Sterile alpha motif) (326 - 386)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 446 a.a.
Protein Preferred Names Protein Names

sterile alpha motif domain-containing protein 7

  • SAM domain-containing protein 7

SAMD7 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
SAMD7 Q7Z3H4 KIF1B Homo sapiens O60333-2
Y2H Array
32814053
Intra
SAMD7 Q7Z3H4 KIF1B Homo sapiens O60333-2
Validated Y2H
32814053
Intra
SAMD7 Q7Z3H4 KIF1B Homo sapiens O60333-2
Y2H Pooling
32814053
Intra
SAMD7 Q7Z3H4 KRTAP6-2 Homo sapiens Q3LI66
Y2H Prey Pooling
32296183
Intra
SAMD7 Q7Z3H4 KRTAP6-2 Homo sapiens Q3LI66
Y2H Array
32296183
Intra
SAMD7 Q7Z3H4 FAM168B Homo sapiens A1KXE4-2
Y2H Array
32296183
Intra
SAMD7 Q7Z3H4 FAM168B Homo sapiens A1KXE4-2
Y2H Prey Pooling
32296183
Intra
SAMD7 Q7Z3H4 TSC1 Homo sapiens Q86WV8
Validated Y2H
32296183
Intra
SAMD7 Q7Z3H4 TSC1 Homo sapiens Q86WV8
Y2H Array
32296183
Intra
SAMD7 Q7Z3H4 TSC1 Homo sapiens Q86WV8
Y2H Prey Pooling
32296183
Intra
SAMD7 Q7Z3H4 KRTAP6-3 Homo sapiens Q3LI67
Y2H Prey Pooling
32296183
Intra
SAMD7 Q7Z3H4 KRTAP6-3 Homo sapiens Q3LI67
Y2H Array
32296183
Intra
SAMD7 Q7Z3H4 RNF11 Homo sapiens Q9Y3C5
Y2H Array
32814053
Intra
SAMD7 Q7Z3H4 RNF11 Homo sapiens Q9Y3C5
Y2H Pooling
32814053
Intra
SAMD7 Q7Z3H4 RNF11 Homo sapiens Q9Y3C5
Validated Y2H
32814053
Intra
SAMD7 Q7Z3H4 OIP5 Homo sapiens O43482
Y2H Array
32296183
Intra
SAMD7 Q7Z3H4 OIP5 Homo sapiens O43482
Y2H Prey Pooling
32296183
Intra
SAMD7 Q7Z3H4 WFS1 Homo sapiens O76024
Y2H Array
32814053
Intra
SAMD7 Q7Z3H4 WFS1 Homo sapiens O76024
Y2H Pooling
32814053
Intra
SAMD7 Q7Z3H4 WFS1 Homo sapiens O76024
Validated Y2H
32814053
Intra
SAMD7 Q7Z3H4 KRTAP3-1 Homo sapiens Q9BYR8
Y2H Prey Pooling
32296183
Intra
SAMD7 Q7Z3H4 KRTAP3-1 Homo sapiens Q9BYR8
Validated Y2H
32296183
Intra
SAMD7 Q7Z3H4 KRTAP3-1 Homo sapiens Q9BYR8
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Keratitis, Hereditary

  • Keratitis

  • Autosomal Dominant Keratitis

  • Hereditary Keratitis

  • Dominantly Inherited Keratitis

  • Keratitis Hereditary

  • KERH
Retinitis Pigmentosa

  • RP

  • Rod-Cone Dystrophy

  • Autosomal Recessive Retinitis Pigmentosa

  • Non-Syndromic Retinitis Pigmentosa

  • Pericentral Pigmentary Retinopathy

  • Pigmentary Retinopathy

  • Tapetoretinal Degeneration

  • Rcd

  • Retinitis Pigmentosa Autosomal Recessive

  • ARRP

  • Retinitis Pigmentosa, Autosomal Recessive

  • Retinitis Pigmentosa 1
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12429 SAMD7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta SAMD7 VGNC VGNC:110338
Felis catus SAMD7 VGNC VGNC:64864
Canis familiaris SAMD7 VGNC VGNC:45854
Rattus norvegicus SAMD7 RGD RGD:1308931
Mus musculus SAMD7 MGD MGI:1923203
Bos taurus SAMD7 VGNC VGNC:34275
Others SAMD7 NCBI