Slc35d3 - solute carrier family 35, member D3 Gene

Mus musculus

Also known as Frcl1; 6230421J19Rik

Gene ID: 76157 | Gene type: protein coding

About Slc35d3

Summary

Predicted to enable antiporter activity and pyrimidine nucleotide-sugar transmembrane transporter activity. Acts upstream of or within energy homeostasis and positive regulation of protein exit from endoplasmic reticulum. Located in early endosome and endoplasmic reticulum. Is expressed in midbrain mantle layer and thymus primordium. Orthologous to human SLC35D3 (solute carrier family 35 member D3). [provided by Alliance of Genome Resources, Apr 2022]

Slc35d3 Products(1)

mRNA	Protein	Name
NM_029529.3	NP_083805.1	solute carrier family 35 member D3

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables UDP-glucose transmembrane transporter activity	IDA IDA: Inferred from direct assay	34269178	MGI
enables protein binding	IPI IPI: Inferred from physical interaction	24550737	MGI
enables protein-macromolecule adaptor activity	IDA IDA: Inferred from direct assay	27171858	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in UDP-glucose transmembrane transport	IDA IDA: Inferred from direct assay	34269178	MGI
acts upstream of or within energy homeostasis	IMP IMP: Inferred from mutant phenotype	24550737	MGI
involved in platelet dense granule organization	IMP IMP: Inferred from mutant phenotype	17062724	MGI
involved in positive regulation of autophagy	IMP IMP: Inferred from mutant phenotype	27171858	MGI
acts upstream of or within positive regulation of protein exit from endoplasmic reticulum	IMP IMP: Inferred from mutant phenotype	24550737	MGI
acts upstream of protein exit from endoplasmic reticulum	IMP IMP: Inferred from mutant phenotype	24550737	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in early endosome	IDA IDA: Inferred from direct assay	24550737	MGI
is active in early endosome membrane	IDA IDA: Inferred from direct assay	22611153	MGI
located in endoplasmic reticulum	IDA IDA: Inferred from direct assay	24550737	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

solute carrier family 35 member D3

frc, fringe-like 1

fringe connection-like protein 1

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13203	SLC35D3 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Slc35d3	NCBI	NCBI:340146

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