Tax1bp3 - Tax1 (human T cell leukemia virus type I) binding protein 3 Gene

Mus musculus

Also known as TIP-1; 1300011C24Rik

Gene ID: 76281 | Gene type: protein coding

About Tax1bp3

Summary

Enables beta-catenin binding activity. Involved in negative regulation of Wnt signaling pathway. Acts upstream of or within negative regulation of cell population proliferation. Located in cytoplasm and nucleus. Is expressed in retina. Orthologous to human TAX1BP3 (Tax1 binding protein 3). [provided by Alliance of Genome Resources, Apr 2022]

Tax1bp3 Products(1)

mRNA	Protein	Name
NM_029564.2	NP_083840.1	tax1-binding protein 3

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables beta-catenin binding	IPI IPI: Inferred from physical interaction	12874278	MGI
enables protein binding	IPI IPI: Inferred from physical interaction	12874278	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in negative regulation of Wnt signaling pathway	IDA IDA: Inferred from direct assay	12874278	MGI
acts upstream of or within negative regulation of cell population proliferation	IDA IDA: Inferred from direct assay	12874278	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in cytoplasm	IDA IDA: Inferred from direct assay	12874278	MGI
located in nucleus	IDA IDA: Inferred from direct assay	12874278	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

tax1-binding protein 3

tax interaction protein 1

Tax1bp3 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	Tax1bp3	Q9DBG9	Ctnnb1	Mus musculus	Q02248	IF	12874278
Intra	Tax1bp3	Q9DBG9	Ctnnb1	Mus musculus	Q02248	Y2H	12874278
Intra	Tax1bp3	Q9DBG9	Ctnnb1	Mus musculus	Q02248	Anti Tag CoIP	12874278
Intra	Tax1bp3	Q9DBG9	Ctnnb1	Mus musculus	Q02248	Pull Down	12874278
Cross	Tax1bp3	Q9DBG9	CTNNB1	Homo sapiens	P35222	ITC	18835279
Cross	Tax1bp3	Q9DBG9	CTNNB1	Homo sapiens	P35222	X-Ray Diffraction	18835279

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14228	TAX1BP3 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Tax1bp3	NCBI	NCBI:30851

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