Tax1bp3 - Tax1 (human T cell leukemia virus type I) binding protein 3 Gene

Also Known as TIP-1; 1300011C24Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 76281

Summary

Enables beta-catenin binding activity. Involved in negative regulation of Wnt signaling pathway. Acts upstream of or within negative regulation of cell population proliferation. Located in cytoplasm and nucleus. Is expressed in retina. Orthologous to human TAX1BP3 (Tax1 binding protein 3). [provided by Alliance of Genome Resources, Apr 2022]

Tax1bp3 Products (1)

mRNA Protein Name
NM_029564.2 NP_083840.1 tax1-binding protein 3

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables beta-catenin binding IPI
IPI: Inferred from physical interaction
12874278 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
12874278 MGI
Biological Process GO Annotation Evidence References Source
involved in negative regulation of Wnt signaling pathway IDA
IDA: Inferred from direct assay
12874278 MGI
acts upstream of or within negative regulation of cell population proliferation IDA
IDA: Inferred from direct assay
12874278 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
12874278 MGI
located in nucleus IDA
IDA: Inferred from direct assay
12874278 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

tax1-binding protein 3

  • tax interaction protein 1

Tax1bp3 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Tax1bp3 Q9DBG9 Ctnnb1 Mus musculus Q02248
IF
12874278
Intra
Tax1bp3 Q9DBG9 Ctnnb1 Mus musculus Q02248
Y2H
12874278
Intra
Tax1bp3 Q9DBG9 Ctnnb1 Mus musculus Q02248
Anti Tag CoIP
12874278
Intra
Tax1bp3 Q9DBG9 Ctnnb1 Mus musculus Q02248
Pull Down
12874278
Cross
Tax1bp3 Q9DBG9 CTNNB1 Homo sapiens P35222
ITC
18835279
Cross
Tax1bp3 Q9DBG9 CTNNB1 Homo sapiens P35222
X-Ray Diffraction
18835279
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14228 TAX1BP3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tax1bp3 NCBI NCBI:30851