2. Gene
  3. Slc24a2 - solute carrier family 24 (sodium/potassium/calcium exchanger), member 2 Gene

Slc24a2 - solute carrier family 24 (sodium/potassium/calcium exchanger), member 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Nckx2; 2810021B17Rik; 6330417K15Rik

Gene ID: 76376 | Gene type: protein coding

About Slc24a2

Summary

Enables Calcium Channel activity. Involved in cellular response to high light intensity and cone photoresponse recovery. Acts upstream of or within several processes, including cellular calcium ion homeostasis; learning or memory; and regulation of synaptic plasticity. Located in membrane. Orthologous to human SLC24A2 (solute carrier family 24 member 2). [provided by Alliance of Genome Resources, Apr 2022]

Slc24a2 Products(2)

mRNA Protein Name
NM_001110240.1 NP_001103710.1 sodium/potassium/calcium exchanger 2 isoform 2
NM_172426.2 NP_766014.1 sodium/potassium/calcium exchanger 2 isoform 1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables calcium channel activity IDA
IDA: Inferred from direct assay
16407245 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within calcium ion transport IDA
IDA: Inferred from direct assay
16407245 MGI
acts upstream of or within establishment of localization in cell IDA
IDA: Inferred from direct assay
16407245 MGI
acts upstream of or within intracellular calcium ion homeostasis IMP
IMP: Inferred from mutant phenotype
16407245 MGI
acts upstream of or within learning IMP
IMP: Inferred from mutant phenotype
16407245 MGI
acts upstream of or within long-term synaptic depression IMP
IMP: Inferred from mutant phenotype
16407245 MGI
acts upstream of or within long-term synaptic potentiation IMP
IMP: Inferred from mutant phenotype
16407245 MGI
acts upstream of or within memory IMP
IMP: Inferred from mutant phenotype
16407245 MGI
acts upstream of or within neuron cellular homeostasis IMP
IMP: Inferred from mutant phenotype
16407245 MGI
Cellular Component GO Annotation Evidence Reference Source
located in membrane IDA
IDA: Inferred from direct assay
16407245 MGI
is active in postsynapse IDA
IDA: Inferred from direct assay
26410028 MGI
is active in presynapse IDA
IDA: Inferred from direct assay
26410028 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

sodium/potassium/calcium exchanger 2

Na(+)/K(+)/Ca(2+)-exchange protein 2

retinal cone Na-Ca+K exchanger

solute carrier family 24 member 2

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13085 SLC24A2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS13087 SLC24A4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc24a2 NCBI NCBI:25769