Slc24a2 - solute carrier family 24 (sodium/potassium/calcium exchanger), member 2 Gene

Also Known as Nckx2; 2810021B17Rik; 6330417K15Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 76376

Summary

Enables Calcium Channel activity. Involved in cellular response to high light intensity and cone photoresponse recovery. Acts upstream of or within several processes, including cellular calcium ion homeostasis; learning or memory; and regulation of synaptic plasticity. Located in membrane. Orthologous to human SLC24A2 (solute carrier family 24 member 2). [provided by Alliance of Genome Resources, Apr 2022]

Slc24a2 Products (2)

mRNA Protein Name
NM_001110240.1 NP_001103710.1 sodium/potassium/calcium exchanger 2 isoform 2
NM_172426.2 NP_766014.1 sodium/potassium/calcium exchanger 2 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables calcium channel activity IDA
IDA: Inferred from direct assay
16407245 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within calcium ion transport IDA
IDA: Inferred from direct assay
16407245 MGI
acts upstream of or within establishment of localization in cell IDA
IDA: Inferred from direct assay
16407245 MGI
acts upstream of or within intracellular calcium ion homeostasis IMP
IMP: Inferred from mutant phenotype
16407245 MGI
acts upstream of or within learning IMP
IMP: Inferred from mutant phenotype
16407245 MGI
acts upstream of or within long-term synaptic depression IMP
IMP: Inferred from mutant phenotype
16407245 MGI
acts upstream of or within long-term synaptic potentiation IMP
IMP: Inferred from mutant phenotype
16407245 MGI
acts upstream of or within memory IMP
IMP: Inferred from mutant phenotype
16407245 MGI
acts upstream of or within neuron cellular homeostasis IMP
IMP: Inferred from mutant phenotype
16407245 MGI
Cellular Component GO Annotation Evidence References Source
located in membrane IDA
IDA: Inferred from direct assay
16407245 MGI
is active in postsynapse IDA
IDA: Inferred from direct assay
26410028 MGI
is active in presynapse IDA
IDA: Inferred from direct assay
26410028 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

sodium/potassium/calcium exchanger 2

  • Na(+)/K(+)/Ca(2+)-exchange protein 2

  • retinal cone Na-Ca+K exchanger

  • solute carrier family 24 member 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13085 SLC24A2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS13087 SLC24A4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc24a2 NCBI NCBI:25769