Mib2 - mindbomb E3 ubiquitin protein ligase 2 Gene

Also Known as skd; Zzank1; 2210008I11Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 76580

Summary

Enables ubiquitin protein Ligase activity. Acts upstream of or within protein ubiquitination. Located in early endosome. Part of ubiquitin Ligase complex. Is expressed in several structures, including 4th ventricle choroid plexus; genitourinary system; gut; hair follicle; and hemolymphoid system gland. Orthologous to human MIB2 (MIB E3 ubiquitin protein Ligase 2). [provided by Alliance of Genome Resources, Apr 2022]

Mib2 Products (11)

mRNA Protein Name
NM_001256107.1 NP_001243036.1 E3 ubiquitin-protein ligase MIB2 isoform 1
NM_001256108.2 NP_001243037.2 E3 ubiquitin-protein ligase MIB2 isoform 2
NM_001369161.1 NP_001356090.1 E3 ubiquitin-protein ligase MIB2 isoform 1
NM_001369162.1 NP_001356091.1 E3 ubiquitin-protein ligase MIB2 isoform 2
NM_001369163.1 NP_001356092.1 E3 ubiquitin-protein ligase MIB2 isoform 2
NM_001369164.1 NP_001356093.1 E3 ubiquitin-protein ligase MIB2 isoform 3
NM_001369165.1 NP_001356094.1 E3 ubiquitin-protein ligase MIB2 isoform 3
NM_001369166.1 NP_001356095.1 E3 ubiquitin-protein ligase MIB2 isoform 4
NM_001369167.1 NP_001356096.1 E3 ubiquitin-protein ligase MIB2 isoform 5
NM_001369168.1 NP_001356097.1 E3 ubiquitin-protein ligase MIB2 isoform 6
NM_145124.3 NP_660106.2 E3 ubiquitin-protein ligase MIB2 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
34635817 MGI
enables ubiquitin protein ligase activity IDA
IDA: Inferred from direct assay
15824097 MGI
enables ubiquitin-protein transferase activity IDA
IDA: Inferred from direct assay
34635817 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within protein ubiquitination IDA
IDA: Inferred from direct assay
15824097 MGI
involved in protein ubiquitination IDA
IDA: Inferred from direct assay
34635817 MGI
Cellular Component GO Annotation Evidence References Source
located in early endosome IDA
IDA: Inferred from direct assay
15824097 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
34635817 MGI
part of ubiquitin ligase complex IDA
IDA: Inferred from direct assay
15824097 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase MIB2

  • RING-type E3 ubiquitin transferase MIB2

  • dyslike

  • dystrophin-like protein

  • mind bomb-2

  • mindbomb homolog 2

  • skeletrophin

  • zinc finger, ZZ type with ankyrin repeat domain 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08423 MIB2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mib2 NCBI NCBI:142678