Jade2 - jade family PHD finger 2 Gene

Also Known as Phf15; mKIAA0239; 1200017K05Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 76901

Summary

Enables ubiquitin protein Ligase activity. Acts upstream of or within SMAD protein signal transduction; generation of neurons; and protein ubiquitination. Predicted to be located in nucleoplasm. Predicted to be part of Histone Acetyltransferase complex. Is expressed in bladder; male associated reproductive structure; testis; ureter; and urethra of male. Orthologous to human JADE2 (jade family PHD finger 2). [provided by Alliance of Genome Resources, Apr 2022]

Jade2 Products (2)

mRNA Protein Name
NM_001357588.3 NP_001344517.1 E3 ubiquitin-protein ligase Jade-2 isoform 1
NM_199299.5 NP_955003.2 E3 ubiquitin-protein ligase Jade-2 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25018020 MGI
enables ubiquitin protein ligase activity IDA
IDA: Inferred from direct assay
25018020 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within neuron projection extension IGI
IGI: Inferred from genetic interaction
25018020 MGI
acts upstream of or within positive regulation of neurogenesis IDA
IDA: Inferred from direct assay
25018020 MGI
acts upstream of or within positive regulation of neurogenesis IMP
IMP: Inferred from mutant phenotype
25018020 MGI
acts upstream of or within protein autoubiquitination IDA
IDA: Inferred from direct assay
25018020 MGI
acts upstream of or within protein polyubiquitination IDA
IDA: Inferred from direct assay
25018020 MGI
acts upstream of or within protein polyubiquitination IMP
IMP: Inferred from mutant phenotype
25018020 MGI
acts upstream of or within regulation of neurogenesis IGI
IGI: Inferred from genetic interaction
25018020 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase Jade-2

  • PHD finger protein 15

  • jade family PHD finger protein 2

  • protein Jade-2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07010 JADE2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Jade2 NCBI NCBI:23338