Col25a1 - collagen, type XXV, alpha 1 Gene

Also Known as CLAC-P; 2700062B08Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 77018

Summary

Predicted to enable amyloid-beta binding activity; heparin binding activity; and identical protein binding activity. Predicted to be an extracellular matrix structural constituent. Acts upstream of or within axonogenesis involved in innervation. Located in collagen-containing extracellular matrix. Is expressed in retina layer and ureter. Human ortholog(s) of this gene implicated in congenital fibrosis of the extraocular muscles 5. Orthologous to human COL25A1 (Collagen type XXV alpha 1 chain). [provided by Alliance of Genome Resources, Apr 2022]

Col25a1 Products (3)

mRNA Protein Name
NM_001244952.1 NP_001231881.1 collagen alpha-1(XXV) chain isoform 3
NM_029838.4 NP_084114.2 collagen alpha-1(XXV) chain isoform 1
NM_198711.3 NP_942004.1 collagen alpha-1(XXV) chain isoform 2

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within axonogenesis involved in innervation IMP
IMP: Inferred from mutant phenotype
24453327 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

collagen alpha-1(XXV) chain

  • collagen-like Alzheimer amyloid plaque component

  • procollagen, type XXV, alpha 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02977 COL25A1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Col25a1 NCBI NCBI:84570