ZNF225 - zinc finger protein 225 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 7768

About ZNF225

This gene has 6 transcripts (splice variants), 25 orthologues and 174 paralogues. Ubiquitous expression in ovary (RPKM 1.5), testis (RPKM 1.4) and 25 other tissues.

Summary

Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

ZNF225 Products (2)

mRNA Protein Name
NM_001321685.2 NP_001308614.1 zinc finger protein 225
NM_013362.4 NP_037494.2 zinc finger protein 225

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32814053 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ZNF225 Protein Structure

KRAB

KRAB: KRAB box (8 - 48)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (190 - 214)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (218 - 242)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (247 - 270)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (275 - 298)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (302 - 325)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (330 - 353)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (358 - 381)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (386 - 411)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (417 - 439)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (443 - 465)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (471 - 494)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (499 - 522)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (527 - 550)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (554 - 579)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (585 - 606)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (614 - 633)

  • 0
  • 200
  • 400
  • 600
  • 706 a.a.
Protein Preferred Names Protein Names

zinc finger protein 225

ZNF225 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
ZNF225 Q9UK10 WFS1 Homo sapiens O76024
Validated Y2H
32814053
Intra
ZNF225 Q9UK10 WFS1 Homo sapiens O76024
Y2H Array
32814053
Intra
ZNF225 Q9UK10 WFS1 Homo sapiens O76024
Y2H Pooling
32814053
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04215 EGR1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16112 ZNF225 Human Pre-designed siRNA Set A Pre-designed Set / Unkown