Msl2 - MSL complex subunit 2 Gene

Also Known as Msl2l1; Rnf184; E130103E02Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 77853

Summary

Predicted to enable ubiquitin protein Ligase activity. Predicted to be involved in histone H4-K16 acetylation and protein ubiquitination. Predicted to be part of MSL complex. Is expressed in embryo. Orthologous to human MSL2 (MSL complex subunit 2). [provided by Alliance of Genome Resources, Apr 2022]

Msl2 Products (2)

mRNA Protein Name
NM_001100451.2 NP_001093921.1 E3 ubiquitin-protein ligase MSL2 isoform 1
NM_001379344.1 NP_001366273.1 E3 ubiquitin-protein ligase MSL2 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables histone H2B ubiquitin ligase activity IMP
IMP: Inferred from mutant phenotype
38030723 MGI
enables promoter-enhancer loop anchoring activity IMP
IMP: Inferred from mutant phenotype
38030723 MGI
Biological Process GO Annotation Evidence References Source
involved in epigenetic regulation of gene expression IMP
IMP: Inferred from mutant phenotype
38030723 MGI
involved in positive regulation of DNA-templated transcription IMP
IMP: Inferred from mutant phenotype
24842875 MGI
Cellular Component GO Annotation Evidence References Source
part of MSL complex IDA
IDA: Inferred from direct assay
24842875 MGI
part of MSL complex IMP
IMP: Inferred from mutant phenotype
38030723 MGI
is active in nucleus IMP
IMP: Inferred from mutant phenotype
38030723 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase MSL2

  • E3 ubiquitin-protein transferase MSL2

  • MSL2-like 1

  • male-specific lethal 2 homolog

  • male-specific lethal 2-like 1

  • male-specific lethal-2 homolog 1

  • ring finger protein 184

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08717 MSL2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Msl2 NCBI NCBI:55167