Lpar4 - lysophosphatidic acid receptor 4 Gene

Also Known as LPA4; p2y9; Gpr23; 5730485F04Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 78134

About Lpar4

Chromosome X: 105,964,231-105,977,506 forward strand.GRCm39:CM001013.3

This gene has 1 transcript (splice variant), 174 orthologues, 16 paralogues and is associated with 22 phenotypes. Biased expression in limb E14.5 (RPKM 7.9), CNS E11.5 (RPKM 2.4) and 1 other tissues.

Summary

Enables lysophosphatidic acid binding activity and lysophosphatidic acid receptor activity. Predicted to be involved in positive regulation of Rho protein signal transduction and positive regulation of cytosolic calcium ion concentration involved in Phospholipase C-activating G protein-coupled signaling pathway. Predicted to act upstream of or within signal transduction. Located in plasma membrane. Is expressed in several structures, including branchial arch; future brain; limb; nose; and skeleton. Orthologous to human LPAR4 (lysophosphatidic acid receptor 4). [provided by Alliance of Genome Resources, Apr 2022]

Lpar4 Products (1)

mRNA Protein Name
NM_175271.4 NP_780480.2 lysophosphatidic acid receptor 4

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables lysophosphatidic acid binding IDA
IDA: Inferred from direct assay
17166850 MGI
enables lysophosphatidic acid receptor activity IDA
IDA: Inferred from direct assay
17166850 MGI
Cellular Component GO Annotation Evidence References Source
located in plasma membrane IDA
IDA: Inferred from direct assay
17166850 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Lpar4 Protein Structure

7tmA_LPAR4

7tmA_LPAR4: cd15155 (39 - 66)

7tmA_LPAR4

7tmA_LPAR4: cd15155 (39 - 321)

7tmA_LPAR4

7tmA_LPAR4: cd15155 (73 - 98)

7tmA_LPAR4

7tmA_LPAR4: cd15155 (110 - 140)

7tmA_LPAR4

7tmA_LPAR4: cd15155 (152 - 174)

7tmA_LPAR4

7tmA_LPAR4: cd15155 (200 - 229)

7tmA_LPAR4

7tmA_LPAR4: cd15155 (241 - 271)

7tmA_LPAR4

7tmA_LPAR4: cd15155 (289 - 314)

  • 0
  • 100
  • 200
  • 300
  • 370 a.a.
Protein Preferred Names Protein Names

lysophosphatidic acid receptor 4

  • G protein-coupled receptor 23

  • LPA receptor 4

  • LPA-4

  • P2Y purinoceptor 9

  • purinergic receptor 9

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07755 LPAR4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS07756 Lpar4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS07757 Lpar4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lpar4 NCBI NCBI:2846