Arhgap10 - Rho GTPase activating protein 10 Gene

Also Known as PSGAP; PS-GAP; PSGAP-m; PSGAP-s; A930033B01Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 78514

Summary

Enables GTPase activator activity. Involved in negative regulation of apoptotic process. Acts upstream of or within Cytoskeleton organization. Located in cytosol. Is expressed in brain. Orthologous to human ARHGAP10 (Rho GTPase activating protein 10). [provided by Alliance of Genome Resources, Apr 2022]

Arhgap10 Products (6)

mRNA Protein Name
NM_001363417.1 NP_001350346.1 rho GTPase-activating protein 10 isoform 2
NM_001363418.1 NP_001350347.1 rho GTPase-activating protein 10 isoform 3
NM_001363419.1 NP_001350348.1 rho GTPase-activating protein 10 isoform 4
NM_001363420.1 NP_001350349.1 rho GTPase-activating protein 10 isoform 5
NM_001363421.1 NP_001350350.1 rho GTPase-activating protein 10 isoform 6
NM_030113.2 NP_084389.2 rho GTPase-activating protein 10 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables GTPase activator activity IDA
IDA: Inferred from direct assay
11238453 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
11238453 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within cytoskeleton organization IMP
IMP: Inferred from mutant phenotype
11238453 MGI
involved in negative regulation of apoptotic process IMP
IMP: Inferred from mutant phenotype
15471851 MGI
Cellular Component GO Annotation Evidence References Source
located in cytosol IMP
IMP: Inferred from mutant phenotype
15471851 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

rho GTPase-activating protein 10

  • PH and SH3 domain-containing rhoGAP protein

  • rho-type GTPase-activating protein 10

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00912 ARHGAP10 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS00921 ARHGAP21 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Arhgap10 NCBI NCBI:79658