Acap2 - ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 Gene

Mus musculus

Also known as CNT-B2; Centb2; mKIAA0041; 4832442G16; 9530039J15Rik

Gene ID: 78618 | Gene type: protein coding

About Acap2

Summary

Enables phosphatidylinositol-3,5-bisphosphate binding activity and small GTPase binding activity. Predicted to be involved in cellular response to nerve growth factor stimulus and endocytic recycling. Predicted to act upstream of or within actin filament-based process. Predicted to be located in ruffle. Predicted to be active in endosome membrane. Is expressed in several structures, including adipose tissue; brain; genitourinary system; liver; and spleen. Orthologous to human ACAP2 (ArfGAP with coiled-coil, ankyrin repeat and PH domains 2). [provided by Alliance of Genome Resources, Apr 2022]

Acap2 Products(1)

mRNA	Protein	Name
NM_030138.2	NP_084414.1	arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables phosphatidylinositol-3,5-bisphosphate binding	IDA IDA: Inferred from direct assay	11001876	MGI
enables protein binding	IPI IPI: Inferred from physical interaction	23572513	MGI
enables small GTPase binding	IPI IPI: Inferred from physical interaction	23572513	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2

centaurin, beta 2

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00134	ACAP2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Acap2	NCBI	NCBI:23527

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