ACAP2 - ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 Gene

Homo sapiens

Also known as CENTB2; CNT-B2

Gene ID: 23527 | Gene type: protein coding

About ACAP2

Cytogenetic location: 3q29 Genomic coordinates (GRCh38): 3:195,274,745-195,443,020 (from NCBI)

This gene has 15 transcripts (splice variants), 212 orthologues and 28 paralogues. Ubiquitous expression in thyroid (RPKM 13.3), lymph node (RPKM 12.2) and 25 other tissues.

Summary

Enables GTPase activator activity. Acts upstream of or within actin filament-based process. Located in ruffle. [provided by Alliance of Genome Resources, Apr 2022]

ACAP2 Products(1)

mRNA	Protein	Name
NM_012287.6	NP_036419.3	arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2

ACAP2 Protein Structure

ArfGap

Ank_2

0
200
400
600
778 a.a.

Protein Preferred Names

Protein Names

arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2

Arf GAP with coiled coil, ANK repeat and PH domains 2

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00134	ACAP2 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	ACAP2	MGD	MGI:1925868
Canis familiaris	ACAP2	VGNC	VGNC:53055
Felis catus	ACAP2	VGNC	VGNC:59498
Rattus norvegicus	ACAP2	RGD	RGD:1562939
Bos taurus	ACAP2	VGNC	VGNC:25527
Macaca mulatta	ACAP2	VGNC	VGNC:69428

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