2. Gene
  3. ACAP3 - ArfGAP with coiled-coil, ankyrin repeat and PH domains 3 Gene

ACAP3 - ArfGAP with coiled-coil, ankyrin repeat and PH domains 3 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as CENTB5

Gene ID: 116983 | Gene type: protein coding

About ACAP3

This gene has 13 transcripts (splice variants), 274 orthologues and 28 paralogues. Ubiquitous expression in skin (RPKM 16.2), brain (RPKM 12.8) and 24 other tissues.

Summary

Predicted to enable GTPase activator activity and metal ion binding activity. Predicted to be involved in regulation of catalytic activity. Predicted to act upstream of or within neuron migration and regulation of neuron projection development. Predicted to be located in growth cone. [provided by Alliance of Genome Resources, Apr 2022]

ACAP3 Products(1)

mRNA Protein Name
NM_030649.3 NP_085152.2 arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 3

ACAP3 Protein Structure

PH

PH: PH domain (269 - 362)

ArfGap

ArfGap: Putative GTPase activating protein for Arf (404 - 520)

Ank_2

Ank_2: Ankyrin repeats (3 copies) (673 - 764)

  • 0
  • 200
  • 400
  • 600
  • 834 a.a.
Protein Preferred Names Protein Names

arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 3

centaurin-beta-5

Related Diseases

Diseases Alias
Osteosclerotic Myeloma
Brachial Plexus Neuritis

Brachial Neuritis

Parsonage-Aldren-Turner Syndrome
Recessive Dystrophic Epidermolysis Bullosa

Autosomal Recessive Dystrophic Epidermolysis Bullosa Generalisata Gravis

Autosomal Recessive Dystrophic Epidermolysis Bullosa, Hallopeau-Siemens Type

Rdeb, Hallopeau-Siemens Type

Severe Generalized Rdeb

Severe Generalized Recessive Dystrophic Epidermolysis Bullosa

Rdeb Generalisata Gravis

Rdeb, Severe Generalized

Rdeb-Sev Gen

Recessive Dystrophic Epidermolysis Bullosa, Severe Generalized

Hallopeau-Siemens Disease
Non-Syndromic X-Linked Intellectual Disability

X-Linked Non-Syndromic Intellectual Disability

Non-Specific X-Linked Mental Retardation

X-Linked Non-Specific Intellectual Disability
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00135 ACAP3 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus ACAP3 VGNC VGNC:59499
Canis familiaris ACAP3 VGNC VGNC:37497
Bos taurus ACAP3 VGNC VGNC:25528
Mus musculus ACAP3 MGD MGI:2153589
Rattus norvegicus ACAP3 RGD RGD:1310711
Macaca mulatta ACAP3 VGNC VGNC:69434