ACAP2 Antibody (YA2485)
(Synonyms: CENTB2; CNT-B2)ACAP2 Antibody (YA2485) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ACAP2.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB
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Reactivity :
Human, Hamster, Rat
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Formulation:
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
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Conjugation:
Non-conjugated
Applications
| Application |
WB
WB: Western Blot
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|---|---|
| Dilution Ratio | 1:500-1:1000 |
Product Details
ACAP2 Antibody (YA2485) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ACAP2.
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Host Rabbit
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Clonality Recombinant, Monoclonal
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Species ReactivityHuman, Hamster, Rat
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Observed Molecular WeightObserved band size: 88 kDaNote: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 88 kDa
Entrez Gene: 23527 Human ; 78618 Mouse ; 619382 Rat
SwissProt: Q15057 Human ; Q6ZQK5 Mouse ; Q5FVC7 Rat
OMIM: 607766 Human
A synthetic peptide of human Centaurin beta 2 aa696-710.
Endogenous
Affinity Purified
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
ACAP2 is a GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6). Doesn't show GAP activity for RAB35[1].
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Subcellular Localization
Cell membrane; Endosome membrane; Peripheral membrane protein
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Expression
Tissue_specificity:Widely expressed. Highest level in lung -
Subunit
Interacts (via KANK domains) with RAB35 (GTP-bound form); the interaction is direct and probably recruits ACAP2 to membranes including plasma membrane (PubMed:30905672). Interacts with MICALL1; the interaction is indirect through RAB35 (By similarity)
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SwissProt ID
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Synonyms
CENTB2; CNT-B2
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Research Field
Signal Transduction
Documentation