Ncapd3 - non-SMC condensin II complex, subunit D3 Gene

Also Known as mKIAA0056; 2810487N22Rik; 4632407J06Rik; B130055D15Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 78658

Summary

Predicted to enable methylated histone binding activity. Acts upstream of or within meiotic chromosome separation. Located in germinal vesicle and kinetochore. Part of condensin complex. Human ortholog(s) of this gene implicated in primary autosomal recessive microcephaly. Orthologous to human NCAPD3 (non-SMC condensin II complex subunit D3). [provided by Alliance of Genome Resources, Apr 2022]

Ncapd3 Products (2)

mRNA Protein Name
NM_001382847.1 NP_001369776.1 condensin-2 complex subunit D3 isoform 2
NM_178113.4 NP_835214.2 condensin-2 complex subunit D3 isoform 1

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within meiotic chromosome separation IMP
IMP: Inferred from mutant phenotype
21795393 MGI
involved in positive regulation of chromosome segregation IMP
IMP: Inferred from mutant phenotype
25474630 MGI
involved in positive regulation of chromosome separation IMP
IMP: Inferred from mutant phenotype
21795393 MGI
Cellular Component GO Annotation Evidence References Source
located in condensed chromosome IDA
IDA: Inferred from direct assay
21795393 MGI
located in condensed nuclear chromosome IDA
IDA: Inferred from direct assay
25474630 MGI
part of condensin complex IDA
IDA: Inferred from direct assay
21795393 MGI
located in germinal vesicle IDA
IDA: Inferred from direct assay
21795393 MGI
located in kinetochore IDA
IDA: Inferred from direct assay
21795393 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

condensin-2 complex subunit D3

  • Jacobsen syndrome region 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09067 NCAPD3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ncapd3 NCBI NCBI:23310