Zc3hav1 - zinc finger CCCH type, antiviral 1 Gene

Also Known as ZAP; ARTD13; PARP13; D6Bwg1452e; 1200014N16Rik; 2900058M19Rik; 9130009D18Rik; 9830115L13Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 78781

Summary

Predicted to enable DEAD/H-box RNA helicase binding activity; RNA binding activity; and identical protein binding activity. Acts upstream of or within cellular response to exogenous dsRNA and positive regulation of type I interferon production. Located in late endosome; lysosome; and nucleus. Is expressed in early conceptus; inner cell mass; liver lobe; oocyte; and thymus primordium. Orthologous to human ZC3HAV1 (zinc finger CCCH-type containing, Antiviral 1). [provided by Alliance of Genome Resources, Apr 2022]

Zc3hav1 Products (3)

mRNA Protein Name
NM_001347122.1 NP_001334051.1 zinc finger CCCH-type antiviral protein 1 isoform 3
NM_028421.1 NP_082697.1 zinc finger CCCH-type antiviral protein 1 isoform 1
NM_028864.2 NP_083140.1 zinc finger CCCH-type antiviral protein 1 isoform 2

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence Verweise Source
acts upstream of or within cellular response to exogenous dsRNA IDA
IDA: Inferred from direct assay
21102435 MGI
acts upstream of or within positive regulation of type I interferon production IDA
IDA: Inferred from direct assay
21102435 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

zinc finger CCCH-type antiviral protein 1

  • ADP-ribosyltransferase diphtheria toxin-like 13

  • inactive Poly [ADP-ribose] polymerase 13

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS15997 ZC3HAV1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22055 Zc3hav1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28573 Zc3hav1 Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Zc3hav1 NCBI NCBI:56829