Hhex - hematopoietically expressed homeobox Gene

Rattus norvegicus

Also known as Hex

Gene ID: 79237 | Gene type: protein coding

About Hhex

Summary

Enables sequence-specific DNA binding activity. Involved in several processes, including negative regulation of transcription, DNA-templated; response to peptide hormone; and response to wounding. Located in nucleus. Orthologous to human HHEX (hematopoietically expressed homeobox). [provided by Alliance of Genome Resources, Apr 2022]

Hhex Products(1)

mRNA	Protein	Name
NM_024385.2	NP_077361.1	hematopoietically-expressed homeobox protein HHEX

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	Reference	Source
enables sequence-specific DNA binding	IDA IDA: Inferred from direct assay	11139473	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in cell differentiation	IDA IDA: Inferred from direct assay	10085234	RGD
involved in negative regulation of DNA-templated transcription	IDA IDA: Inferred from direct assay	10085234	RGD
involved in negative regulation of angiogenesis	IDA IDA: Inferred from direct assay	15016828	RGD
involved in negative regulation of transcription by RNA polymerase II	IDA IDA: Inferred from direct assay	15016828	RGD
involved in negative regulation of vascular endothelial growth factor receptor signaling pathway	IDA IDA: Inferred from direct assay	15016828	RGD
involved in response to peptide hormone	IEP IEP: Inferred from expression pattern	10871399	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

hematopoietically-expressed homeobox protein HHEX

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS06159	HHEX Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Hhex	NCBI	NCBI:3087

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