2. Gene
  3. Hsd17b2 - hydroxysteroid (17-beta) dehydrogenase 2 Gene

Hsd17b2 - hydroxysteroid (17-beta) dehydrogenase 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 79243 | Gene type: protein coding

About Hsd17b2

Summary

Enables estradiol 17-beta-dehydrogenase activity and testosterone dehydrogenase (NAD+) activity. Involved in bone development; cellular response to metal ion; and steroid hormone biosynthetic process. Located in intracellular membrane-bounded organelle. Orthologous to human HSD17B2 (hydroxysteroid 17-beta dehydrogenase 2). [provided by Alliance of Genome Resources, Apr 2022]

Hsd17b2 Products(1)

mRNA Protein Name
NM_024391.2 NP_077367.2 estradiol 17-beta-dehydrogenase 2
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables estradiol 17-beta-dehydrogenase [NAD(P)+] activity IDA
IDA: Inferred from direct assay
8612487 RGD
enables testosterone dehydrogenase (NAD+) activity IDA
IDA: Inferred from direct assay
8612487 RGD
Biological Process GO Annotation Evidence Reference Source
involved in androgen biosynthetic process IDA
IDA: Inferred from direct assay
8612487 RGD
involved in bone development IEP
IEP: Inferred from expression pattern
15012600 RGD
involved in cellular response to metal ion IEP
IEP: Inferred from expression pattern
18602937 RGD
involved in estrogen biosynthetic process IDA
IDA: Inferred from direct assay
8612487 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

estradiol 17-beta-dehydrogenase 2

17-beta-HSD 2

17-beta-hydroxysteroid dehydrogenase 2

17-beta-hydroxysteroid dehydrogenase type 2

testosterone 17-beta-dehydrogenase

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06395 HSD17B2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hsd17b2 NCBI NCBI:3294