2. Gene
  3. Htr3a - 5-hydroxytryptamine receptor 3A Gene

Htr3a - 5-hydroxytryptamine receptor 3A Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as 5HT3; Htr3; 5-HT3; 5-HT3A

Gene ID: 79246 | Gene type: protein coding

About Htr3a

Primary_assembly 8: 49,242,020-49,254,389 reverse strand.mRatBN7.2:CM026981.1

This gene has 3 transcripts (splice variants), 215 orthologues, 41 paralogues and is associated with 6 phenotypes. Biased expression in Brain (RPKM 17.), Testes (RPKM 1.3) and 1 other tissue.

Summary

Enables serotonin-gated cation-selective channel activity. Involved in several processes, including positive regulation of ion transmembrane transporter activity; response to cocaine; and response to ethanol. Located in several cellular components, including axon; neuronal cell body; and plasma membrane. Is active in glutamatergic synapse. Is integral component of postsynaptic membrane and integral component of presynaptic membrane. Human ortholog(s) of this gene implicated in irritable bowel syndrome. Orthologous to human HTR3A (5-hydroxytryptamine receptor 3A). [provided by Alliance of Genome Resources, Apr 2022]

Htr3a Products(1)

mRNA Protein Name
NM_024394.3 NP_077370.2 5-hydroxytryptamine receptor 3A precursor

Htr3a Protein Structure

LIC

LIC: TIGR00860 (4 - 481)

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  • 488 a.a.
Protein Preferred Names Protein Names

5-hydroxytryptamine receptor 3A

5-HT-3

5-HT3 receptor

5-HT3-A

5-HT3R

5-hydroxytryptamine (serotonin) receptor 3A, ionotropic

5-hydroxytryptamine receptor 3

serotonin receptor 3A

serotonin-gated ion channel receptor

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06470 HTR3A Human Pre-designed siRNA Set A / Unkown
HY-RS06471 Htr3a Mouse Pre-designed siRNA Set A / Unkown
HY-RS06472 Htr3a Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Htr3a NCBI NCBI:3359