S100G - S100 calcium binding protein G Gene

Also Known as CABP; CABP1; CALB3; CABP9K

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 795

About S100G

Cytogenetic location: Xp22.2 Genomic coordinates (GRCh38): X:16,650,158-16,654,670 (from NCBI)

This gene has 1 transcript (splice variant), 338 orthologues and 21 paralogues. Restricted expression toward duodenum (RPKM 36.4).

Summary

This gene encodes calbindin D9K, a vitamin D-dependent calcium-binding protein. This cytosolic protein belongs to a family of calcium-binding proteins that includes Calmodulin, parvalbumin, troponin C, and S100 protein. In the intestine, the protein is vitamin D-dependent and its expression correlates with calcium transport activity. The protein may increase Ca2+ absorption by buffering Ca2+ in the cytoplasm and increase ATP-dependent Ca2+ transport in duodenal basolateral membrane vesicles. [provided by RefSeq, Jul 2008]

S100G Products (1)

mRNA Protein Name
NM_004057.3 NP_004048.1 protein S100-G

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

S100G Protein Structure

S_100

S_100: S-100/ICaBP type calcium binding domain (10 - 45)

EF-hand_1

EF-hand_1: EF hand (50 - 76)

  • 0
  • 79 a.a.
Protein Preferred Names Protein Names

protein S100-G

  • calbindin 3, (vitamin D-dependent calcium-binding protein)

S100G Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
S100G P29377 NSMF Homo sapiens Q6X4W1-2
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Granulomatous Endometritis
Noonan Syndrome 7

  • NS7

  • Noonan Syndrome, Type 7
Spinocerebellar Ataxia 1

  • Spinocerebellar Ataxia Type 1

  • SCA1

  • Olivopontocerebellar Atrophy I

  • Opca1

  • Opca4

  • Menzel Type Opca

  • Schut-Haymaker Type Opca

  • Spinocerebellar Atrophy I

  • Opca I

  • Olivopontocerebellar Atrophy Iv

  • Opca Iv

  • Cerebelloparenchymal Disorder I

  • Cpd1

  • Olivopontocerebellar Atrophy 1

  • Cerebelloparenchymal Disorder 1

  • Olivopontocerebellar Atrophy 4

  • Spinocerebellar Atrophy 1

  • Type 1 Spinocerebellar Ataxia

  • Spinocerebellar Ataxia-1

  • Ataxia, Spinocerebellar, Type 1
Vitamin D Hydroxylation-Deficient Rickets, Type 1a

  • Vitamin D-Dependent Rickets, Type 1a

  • Vitamin D-Dependent Rickets, Type 1

  • VDDR1A

  • 25-Hydroxycholecalciferol-1-Hydroxylase Deficiency

  • 1-Alpha-Hydroxylase Deficiency

  • Vdd1

  • Pddr1a

  • Pddr Ia

  • Vitamin D-Dependent Rickets, Type I

  • Vitamin D-Dependent Rickets Type 1a

  • 1-Alpha, 25-Hydroxyvitamin D3 Deficiency, Selective

  • Vitamin D Dependency, Type 1

  • Pseudovitamin D-Deficiency Rickets, Type Ia

  • Rickets Vitamin D-Dependent 1a

  • 1-Alpha 25-Hydroxyvitamin D3 Deficiency Selective

  • Pddr

  • Pseudovitamin D Deficiency Rickets

  • Pseudovitamin D-Deficiency Rickets Type Ia

  • Vitamin D Dependency Type 1
Schnyder Corneal Dystrophy

  • Schnyder Crystalline Corneal Dystrophy

  • SCCD

  • Corneal Dystrophy, Crystalline, Of Schnyder

  • Corneal Dystrophy, Schnyder Type

  • Corneal Dystrophy Crystalline Of Schnyder

  • Crystalline Stromal Dystrophy

  • Hereditary Crystalline Stromal Dystrophy Of Schnyder

  • Scd

  • Corneal Dystrophy, Schnyder

  • Schnyder Crystalline Dystrophy Sine Crystals

  • Dystrophy, Corneal, Crystalline, Schnyder
Vitamin D-Dependent Rickets, Type 2a

  • Hvdrr

  • Generalized Resistance To 1,25-Dihydroxyvitamin D

  • Hypocalcemic Vitamin D-Resistant Rickets

  • VDDR2A

  • Rickets, Hereditary Vitamin D-Resistant

  • Vitamin D-Resistant Rickets With End-Organ Unresponsiveness To 1,25-Dihydroxycholecalciferol

  • Pddr Iia

  • Rickets-Alopecia Syndrome

  • Rickets, Vitamin D-Resistant, Type Iia

  • Vitamin D-Dependent Rickets Type 2a

  • Vitamin D-Dependent Rickets, Type 2

  • Vitamin D-Dependent Rickets, Type 2a, With Or Without Alopecia

  • Generalized 1,25-Dihydroxyvitamin D

  • Pseudovitamin D-Deficiency, Type Iia

  • Hereditary Vitamin D-Resistant Rickets

  • Vddr Ii

  • Vdrr Ii

  • Vitamin D-Dependent Rickets Type Ii

  • Vitamin D-Resistant Rickets Type Ii

  • Rickets Vitamin D-Dependent 2a

  • Pseudovitamin D-Deficiency Type Iia

  • Rickets Hereditary Vitamin D-Resistant

  • Type Iia Rickets

  • Vitamin D-Dependent Rickets Type 2a With Or Without Alopecia

  • Vitamin D-Dependent Rickets, Type Ii

  • Familial Hypophosphatemic Rickets

  • Hypophosphatemic Rickets, X-Linked Dominant
Vitamin D-Dependent Rickets

  • Vddr
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12388 S100G Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus S100G MGD MGI:104528
Rattus norvegicus S100G RGD RGD:2253
Canis familiaris S100G VGNC VGNC:49688
Bos taurus S100G VGNC VGNC:34249
Macaca mulatta S100G VGNC VGNC:77016
Others S100G NCBI