PLEKHS1 - pleckstrin homology domain containing S1 Gene

Also Known as HEL185; C10orf81

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 79949

About PLEKHS1

This gene has 10 transcripts (splice variants), 180 orthologues and 7 paralogues. Biased expression in duodenum (RPKM 10.1), small intestine (RPKM 9.0) and 9 other tissues.

PLEKHS1 Products (5)

mRNA Protein Name
NM_001193434.2 NP_001180363.1 pleckstrin homology domain-containing family S member 1 isoform 2
NM_001193435.2 NP_001180364.1 pleckstrin homology domain-containing family S member 1 isoform 2
NM_001395068.1 NP_001381997.1 pleckstrin homology domain-containing family S member 1 isoform 4
NM_024889.5 NP_079165.3 pleckstrin homology domain-containing family S member 1 isoform 3
NM_182601.2 NP_872407.1 pleckstrin homology domain-containing family S member 1 isoform 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25814554 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PLEKHS1 Protein Structure

PH_11

PH_11: Pleckstrin homology domain (33 - 124)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 465 a.a.
Protein Preferred Names Protein Names

pleckstrin homology domain-containing family S member 1

  • PH domain-containing family S member 1

PLEKHS1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
PLEKHS1 Q5SXH7 PBLD Homo sapiens P30039
Anti Tag CoIP
33961781
Intra
PLEKHS1 Q5SXH7 PBLD Homo sapiens P30039
Anti Tag CoIP
28514442
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Ureter, Cancer Of

  • Ureter Carcinoma

  • Ureter Cancer

  • Ureteral Neoplasms

  • Malignant Neoplasm Of Ureter

  • Malignant Tumour Of Ureter

  • Malignant Ureteral Tumor

  • Ureteral Carcinoma

  • Ureteral Neoplasm
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10702 PLEKHS1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus PLEKHS1 VGNC VGNC:64239
Rattus norvegicus PLEKHS1 RGD RGD:1559884
Mus musculus PLEKHS1 MGD MGI:2443041
Canis familiaris PLEKHS1 VGNC VGNC:44688
Macaca mulatta PLEKHS1 VGNC VGNC:76116
Bos taurus PLEKHS1 VGNC VGNC:33027
Others PLEKHS1 NCBI