2. Gene
  3. Sec61a1 - SEC61 translocon subunit alpha 1 Gene

Sec61a1 - SEC61 translocon subunit alpha 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Sec61a

Gene ID: 80843 | Gene type: protein coding

About Sec61a1

Summary

Predicted to enable several functions, including Calcium Channel activity; protein transmembrane transporter activity; and ribosome binding activity. Involved in response to interferon-gamma. Located in rough endoplasmic reticulum. Human ortholog(s) of this gene implicated in familial juvenile hyperuricemic nephropathy. Orthologous to human SEC61A1 (Sec61 translocon subunit alpha 1). [provided by Alliance of Genome Resources, Apr 2022]

Sec61a1 Products(1)

mRNA Protein Name
NM_199256.2 NP_954865.1 protein transport protein Sec61 subunit alpha isoform 1
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in response to type II interferon IEP
IEP: Inferred from expression pattern
16604358 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein transport protein Sec61 subunit alpha isoform 1

SEC61, alpha subunit

Sec61 alpha 1 subunit

Sec61 alpha subunit homolog

Sec61 translocon alpha 1 subunit

protein transport protein Sec61 subunit alpha

sec61 alpha-1

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-139615 Sec61-IN-1 Inhibitor 99.70% Unkown
HY-RS12621 SEC61A1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sec61a1 NCBI NCBI:29927