Hnrnpl - heterogeneous nuclear ribonucleoprotein L Gene

Also Known as Hnrpl; hnrnp-L

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 80846

Summary

Enables mRNA 3'-UTR binding activity and mRNA CDS binding activity. Involved in several processes, including cellular response to amino acid starvation; positive regulation of mRNA binding activity; and regulation of gene expression. Located in cytosol; nucleus; and perinuclear region of cytoplasm. Human ortholog(s) of this gene implicated in hepatocellular carcinoma; lung cancer; and systemic scleroderma. Orthologous to human HNRNPL (heterogeneous nuclear ribonucleoprotein L). [provided by Alliance of Genome Resources, Apr 2022]

Hnrnpl Products (2)

mRNA Protein Name
NM_001134760.1 NP_001128232.1 heterogeneous nuclear ribonucleoprotein L isoform a
NM_032619.2 NP_116008.2 heterogeneous nuclear ribonucleoprotein L isoform b

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables mRNA 3'-UTR binding IDA
IDA: Inferred from direct assay
15798208 RGD
enables mRNA CDS binding IDA
IDA: Inferred from direct assay
16980303 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
18161049 RGD
Biological Process GO Annotation Evidence References Source
involved in cellular response to amino acid starvation IDA
IDA: Inferred from direct assay
19273590 RGD
involved in circadian rhythm IEP
IEP: Inferred from expression pattern
15798208 RGD
involved in negative regulation of mRNA splicing, via spliceosome IMP
IMP: Inferred from mutant phenotype
22570490 RGD
involved in positive regulation of translation IMP
IMP: Inferred from mutant phenotype
19273590 RGD
involved in response to peptide IEP
IEP: Inferred from expression pattern
12576095 RGD
Cellular Component GO Annotation Evidence References Source
located in perinuclear region of cytoplasm IDA
IDA: Inferred from direct assay
18161049 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

heterogeneous nuclear ribonucleoprotein L

  • heterogenous nuclear ribonucleoprotein L

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06274 HNRNPL Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hnrnpl NCBI NCBI:3191