OR51E2 - olfactory receptor family 51 subfamily E member 2 Gene

Also Known as PSGR; HPRAJ; OR52A2; OR51E3P

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 81285

About OR51E2

Cytogenetic location: 11p15.4 Genomic coordinates (GRCh38): 11:4,680,171-4,697,853 (from NCBI)

This gene has 3 transcripts (splice variants), 108 orthologues and 51 paralogues. Biased expression in prostate (RPKM 29.8) and placenta (RPKM 2.3).

Summary

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The Olfactory Receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The Olfactory Receptor gene family is the largest in the genome. The nomenclature assigned to the Olfactory Receptor genes and proteins for this organism is independent of Other organisms. [provided by RefSeq, Jul 2008]

OR51E2 Products (1)

mRNA Protein Name
NM_030774.4 NP_110401.1 olfactory receptor 5.10E+03

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables nuclear steroid receptor activity IDA
IDA: Inferred from direct assay
19389702 GOA
enables olfactory receptor activity IDA
IDA: Inferred from direct assay
19389702 GOA
enables olfactory receptor activity IMP
IMP: Inferred from mutant phenotype
29249973 GOA
Biological Process GO Annotation Evidence References Source
involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
29249973 GOA
involved in cell migration IMP
IMP: Inferred from mutant phenotype
29249973 GOA
involved in melanocyte differentiation IMP
IMP: Inferred from mutant phenotype
27226631 GOA
involved in melanocyte proliferation IMP
IMP: Inferred from mutant phenotype
27226631 GOA
involved in steroid hormone receptor signaling pathway IDA
IDA: Inferred from direct assay
19389702 GOA
Cellular Component GO Annotation Evidence References Source
located in early endosome membrane IDA
IDA: Inferred from direct assay
27226631 GOA
located in intracellular organelle IDA
IDA: Inferred from direct assay
29249973 GOA
located in plasma membrane IDA
IDA: Inferred from direct assay
23401498 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

OR51E2 Protein Structure

7tm_4

7tm_4: Olfactory receptor (145 - 284)

  • 0
  • 100
  • 200
  • 300
  • 320 a.a.
Protein Preferred Names Protein Names

olfactory receptor 51E2

  • olfactory receptor OR11-16

Related Diseases

Diseases Alias
Prostate Cancer

  • Prostate Carcinoma

  • Prostate Cancer, Familial

  • Prostate Neoplasm

  • Prostate Cancer, Somatic

  • Prostate Cancer, Susceptibility To

  • Prostatic Cancer

  • Prostatic Neoplasms

  • Hereditary Prostate Cancer

  • Prostatic Neoplasm

  • Cancer Of Prostate

  • Carcinoma Of Prostate

  • Familial Prostate Cancer

  • Familial Prostate Carcinoma

  • Malignant Tumor Of Prostate

  • Malignant Neoplasm Of Prostate

  • Prostate Cancer, Familial, Susceptibility To

  • Malignant Tumor Of The Prostate

  • Ngp - New Growth Of Prostate

  • Tumor Of The Prostate

  • Prostate Cancer, Hereditary

  • Cancer Of The Prostate

  • Malignant Neoplasm Of The Prostate

  • Prostatic Carcinoma

  • PC

  • Prca

  • Cancer, Prostate

  • Malignant Prostatic Tumour

  • Malignant Tumour Of Prostate

  • Primary Prostate Cancer

  • Primary Malignant Neoplasm Of Prostate

  • Prostate Gland Cancer
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09818 OR51E2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus OR51E2 VGNC VGNC:101075
Rattus norvegicus OR51E2 RGD RGD:628858
Canis familiaris OR51E2 VGNC VGNC:97040
Mus musculus OR51E2 MGD MGI:2157548
Others OR51E2 NCBI