2. Gene
  3. MARCKSL1 - Marcksl1 MARCKS-like 1 Gene

MARCKSL1 - Marcksl1 MARCKS-like 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as F52; Mlp

Gene ID: 81520 | Gene type: protein coding

About MARCKSL1

Summary

Enables voltage-gated Calcium Channel activity involved in regulation of presynaptic cytosolic calcium levels. Predicted to be involved in actin filament organization and central nervous system development. Predicted to act upstream of or within positive regulation of cell population proliferation. Is active in presynaptic cytosol and synaptic vesicle. Is anchored component of presynaptic membrane. Biomarker of visual epilepsy. Orthologous to human MARCKSL1 (MARCKS like 1). [provided by Alliance of Genome Resources, Apr 2022]

MARCKSL1 Products(1)

mRNA Protein Name
NM_030862.2 NP_110489.1 MARCKS-related protein
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in regulation of presynaptic cytosolic calcium ion concentration IDA
IDA: Inferred from direct assay
16987251 RGD
involved in regulation of presynaptic cytosolic calcium ion concentration IEP
IEP: Inferred from expression pattern
16987251 RGD
involved in regulation of presynaptic cytosolic calcium ion concentration IMP
IMP: Inferred from mutant phenotype
16987251 RGD
Cellular Component GO Annotation Evidence Reference Source
is active in presynaptic cytosol IDA
IDA: Inferred from direct assay
8557647 RGD
is active in presynaptic membrane IDA
IDA: Inferred from direct assay
8557647 RGD
is active in synaptic vesicle IDA
IDA: Inferred from direct assay
8557647 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

MARCKS-related protein

MARCKS-like protein 1

MARCKS-related protein-like

brain protein F52

mac-MARCKS

macMARCKS

macrophage myristoylated alanine-rich C kinase substrate

myristoylated alanine-rich C kinase substrate

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08146 MARCKSL1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens MARCKSL1 NCBI NCBI:65108