2. Gene
  3. Psmc5 - proteasome 26S subunit, ATPase 5 Gene

Psmc5 - proteasome 26S subunit, ATPase 5 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Sug1

Gene ID: 81827 | Gene type: protein coding

About Psmc5

Summary

Enables ATP hydrolysis activity and TBP-class protein binding activity. Involved in modulation of chemical synaptic transmission and positive regulation of inclusion body assembly. Located in inclusion body; nucleus; and postsynapse. Part of cytosolic Proteasome complex and nuclear Proteasome complex. Orthologous to human PSMC5 (Proteasome 26S subunit, ATPase 5). [provided by Alliance of Genome Resources, Apr 2022]

Psmc5 Products(1)

mRNA Protein Name
NM_031149.1 NP_112411.1 26S proteasome regulatory subunit 8
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables ATP hydrolysis activity IDA
IDA: Inferred from direct assay
9287326 RGD
enables TBP-class protein binding IPI
IPI: Inferred from physical interaction
10526239 RGD
Biological Process GO Annotation Evidence Reference Source
involved in positive regulation of inclusion body assembly IMP
IMP: Inferred from mutant phenotype
18986984 RGD
Cellular Component GO Annotation Evidence Reference Source
part of cytosolic proteasome complex IDA
IDA: Inferred from direct assay
18986984 RGD
located in inclusion body IDA
IDA: Inferred from direct assay
18986984 RGD
part of nuclear proteasome complex IDA
IDA: Inferred from direct assay
8710853 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

26S proteasome regulatory subunit 8

26S protease regulatory subunit 8

26S proteasome AAA-ATPase subunit RPT6

TRIP1

for proteasomal ATPase (SUG1)

p45/SUG

peptidase (prosome, macropain) 26S subunit, ATPase 5

protease (prosome, macropain) 26S subunit, ATPase 5

proteasomal ATPase (SUG1)

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11315 PSMC5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22747 Psmc5 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Psmc5 NCBI NCBI:5705