2. Gene
  3. Cacng8 - calcium channel, voltage-dependent, gamma subunit 8 Gene

Cacng8 - calcium channel, voltage-dependent, gamma subunit 8 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus
Gene ID: 81905 | Gene type: protein coding

About Cacng8

Summary

Enables Calcium Channel regulator activity. Involved in regulation of AMPA Receptor activity and regulation of postsynaptic membrane neurotransmitter receptor levels. Located in Schaffer collateral - CA1 synapse; glutamatergic synapse; and postsynaptic density. Is integral component of postsynaptic density membrane. Part of L-type voltage-gated Calcium Channel complex. Is expressed in central nervous system and retina. Orthologous to human CACNG8 (calcium voltage-gated channel auxiliary subunit gamma 8). [provided by Alliance of Genome Resources, Apr 2022]

Cacng8 Products(1)

mRNA Protein Name
NM_133190.3 NP_573453.2 voltage-dependent calcium channel gamma-8 subunit
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables calcium channel regulator activity IDA
IDA: Inferred from direct assay
21127204 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
33981040 MGI
Biological Process GO Annotation Evidence Reference Source
involved in regulation of AMPA receptor activity IDA
IDA: Inferred from direct assay
21172611 MGI
Cellular Component GO Annotation Evidence Reference Source
part of L-type voltage-gated calcium channel complex IDA
IDA: Inferred from direct assay
21127204 MGI
is active in Schaffer collateral - CA1 synapse IDA
IDA: Inferred from direct assay
27076426 MGI
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
36429079 MGI
located in postsynaptic density IDA
IDA: Inferred from direct assay
21172611 MGI
is active in postsynaptic density membrane IDA
IDA: Inferred from direct assay
27076426 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

voltage-dependent calcium channel gamma-8 subunit

TARP gamma-8

neuronal voltage-gated calcium channel gamma-8 subunit

transmembrane AMPAR regulatory protein gamma-8

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS01815 CACNG8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cacng8 NCBI NCBI:59283