Ndst3 - N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3 Gene

Also Known as NDST-3; N-HSST 3; 4921531K01Rik; 4930511P15Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 83398

Summary

Enables deacetylase activity and sulfotransferase activity. Predicted to be involved in heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in Golgi apparatus. Is expressed in several structures, including future brain; genitourinary system; heart; nervous system; and retina. Orthologous to human NDST3 (N-deacetylase and N-sulfotransferase 3). [provided by Alliance of Genome Resources, Apr 2022]

Ndst3 Products (2)

mRNA Protein Name
NM_001293682.1 NP_001280611.1 bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3 isoform 2
NM_031186.3 NP_112463.2 bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables N-acetylglucosamine deacetylase activity IDA
IDA: Inferred from direct assay
11087757 MGI
enables [heparan sulfate]-glucosamine N-sulfotransferase activity IDA
IDA: Inferred from direct assay
11087757 MGI
enables deacetylase activity IDA
IDA: Inferred from direct assay
11087757 MGI
enables sulfotransferase activity IDA
IDA: Inferred from direct assay
11087757 MGI
Biological Process GO Annotation Evidence References Source
involved in heparan sulfate proteoglycan biosynthetic process IMP
IMP: Inferred from mutant phenotype
18385133 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3

  • N-heparan sulfate sulfotransferase 3

  • glucosaminyl N-deacetylase/N-sulfotransferase 3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09120 NDST3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ndst3 NCBI NCBI:9348