Slc22a8 - solute carrier family 22 member 8 Gene

Also Known as OCT3; Oat3; Roct

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 83500

Summary

Enables organic anion transmembrane transporter activity; protein kinase C binding activity; and quaternary ammonium group transmembrane transporter activity. Involved in glutathione transport; quaternary ammonium group transport; and response to organic cyclic compound. Located in apical plasma membrane and basolateral plasma membrane. Orthologous to human SLC22A8 (solute carrier family 22 member 8). [provided by Alliance of Genome Resources, Apr 2022]

Slc22a8 Products (1)

mRNA Protein Name
NM_031332.1 NP_112622.1 organic anion transporter 3

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables organic anion transmembrane transporter activity IDA
IDA: Inferred from direct assay
12679720 RGD
enables protein kinase C binding IPI
IPI: Inferred from physical interaction
19028678 RGD
enables quaternary ammonium group transmembrane transporter activity IDA
IDA: Inferred from direct assay
17616214 RGD
Biological Process GO Annotation Evidence References Source
involved in glutathione transport IDA
IDA: Inferred from direct assay
17719021 RGD
involved in quaternary ammonium group transport IDA
IDA: Inferred from direct assay
17616214 RGD
involved in response to organic cyclic compound IEP
IEP: Inferred from expression pattern
16925582 RGD
Cellular Component GO Annotation Evidence References Source
located in apical plasma membrane IDA
IDA: Inferred from direct assay
18619525 RGD
located in basolateral plasma membrane IDA
IDA: Inferred from direct assay
17971680 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

organic anion transporter 3

solute carrier family 22 member 8

  • organic anion/dicarboxylate exchanger

  • rOat3

  • solute carrier family 22 (organic anion transporter), member 8

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13080 SLC22A8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc22a8 NCBI NCBI:9376