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Tex11 - testis expressed gene 11 Gene

Also Known as ZIP4H; 4930565P14Rik

Species: Mus musculus

Gene Type: protein coding

Gene ID: 83558

Summary

Involved in meiotic gene conversion and reciprocal meiotic recombination. Acts upstream of or within several processes, including fertilization; male gonad development; and meiotic chromosome segregation. Located in central element. Colocalizes with synaptonemal complex. Is expressed in oocyte. Human ortholog(s) of this gene implicated in X-linked spermatogenic failure 2. Orthologous to human TEX11 (testis expressed 11). [provided by Alliance of Genome Resources, Apr 2022]

Tex11 Products (2)

mRNA	Protein	Name
NM_001167997.1	NP_001161469.1	testis-expressed protein 11 isoform 2
NM_031384.2	NP_113561.2	testis-expressed protein 11 isoform 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	References	Source
enables protein binding	IPI IPI: Inferred from physical interaction	18316482	MGI

Biological Process GO Annotation	Evidence	References	Source
acts upstream of apoptotic process	IMP IMP: Inferred from mutant phenotype	18316482	MGI
acts upstream of or within chiasma assembly	IMP IMP: Inferred from mutant phenotype	18316482	MGI
acts upstream of ectopic germ cell programmed cell death	IMP IMP: Inferred from mutant phenotype	18316482	MGI
acts upstream of or within fertilization	IMP IMP: Inferred from mutant phenotype	18316482	MGI
acts upstream of or within male gonad development	IMP IMP: Inferred from mutant phenotype	18316482	MGI
acts upstream of or within male meiosis chromosome segregation	IMP IMP: Inferred from mutant phenotype	18316482	MGI
acts upstream of or within male meiotic nuclear division	IMP IMP: Inferred from mutant phenotype	18316482	MGI
involved in meiotic gene conversion	IMP IMP: Inferred from mutant phenotype	18369460	MGI
acts upstream of or within negative regulation of apoptotic process	IMP IMP: Inferred from mutant phenotype	18316482	MGI
acts upstream of or within negative regulation of developmental process	IMP IMP: Inferred from mutant phenotype	18316482	MGI
acts upstream of or within negative regulation of reproductive process	IMP IMP: Inferred from mutant phenotype	18316482	MGI
involved in reciprocal meiotic recombination	IMP IMP: Inferred from mutant phenotype	18369460	MGI
acts upstream of or within resolution of meiotic recombination intermediates	IMP IMP: Inferred from mutant phenotype	18316482	MGI
acts upstream of or within synaptonemal complex assembly	IMP IMP: Inferred from mutant phenotype	18316482	MGI

Cellular Component GO Annotation	Evidence	References	Source
located in central element	IDA IDA: Inferred from direct assay	18316482	MGI
located in chromosome	IDA IDA: Inferred from direct assay	30272023	MGI
located in condensed nuclear chromosome	IDA IDA: Inferred from direct assay	18316482	MGI
colocalizes with synaptonemal complex	IDA IDA: Inferred from direct assay	18369460	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names	Protein Names
testis-expressed protein 11	protein ZIP4 homolog testis-expressed sequence 11 protein

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14389	TEX11 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Tex11	NCBI	NCBI:56159