2. Gene
  3. Polr1a - RNA polymerase I subunit A Gene

Polr1a - RNA polymerase I subunit A Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Rpa1; Rpo1-4

Gene ID: 83581 | Gene type: protein coding

About Polr1a

Summary

Contributes to DNA-directed 5'-3' RNA polymerase activity. Involved in rRNA transcription. Part of RNA polymerase I complex. Human ortholog(s) of this gene implicated in acrofacial dysostosis Cincinnati type. Orthologous to human POLR1A (RNA polymerase I subunit A). [provided by Alliance of Genome Resources, Apr 2022]

Polr1a Products(1)

mRNA Protein Name
NM_031772.2 NP_113960.2 DNA-directed RNA polymerase I subunit RPA1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
contributes to DNA-directed 5'-3' RNA polymerase activity IDA
IDA: Inferred from direct assay
9422795 RGD
Biological Process GO Annotation Evidence Reference Source
involved in rRNA transcription IDA
IDA: Inferred from direct assay
9422795 RGD
Cellular Component GO Annotation Evidence Reference Source
part of RNA polymerase I complex IDA
IDA: Inferred from direct assay
9422795 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

DNA-directed RNA polymerase I subunit RPA1

A194

DNA-directed RNA polymerase I A

DNA-directed RNA polymerase I largest subunit

DNA-directed RNA polymerase I subunit A

RNA polymerase 1-4

RNA polymerase I 194 kDa subunit

RNA polymerase I subunit A1

RPA194

polymerase (RNA) I polypeptide A

pol

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10837 POLR1A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21909 Polr1a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Polr1a NCBI NCBI:25885